RESUMO
Gorham-Stout disease is a rare disease characterized by osteolysis, angiomatosis, and soft-tissue swelling. It is a diagnosis of exclusion and has an unknown etiology. Chylothorax is a common complication of the disease that is associated with a high mortality rate. There is no standard of treatment. We report a case of a 16-year-old female with Gorham-Stout disease and recurrent pleural effusions who was successfully treated with concurrent zoledronic acid and peg-interferon α-2b.
Assuntos
Conservadores da Densidade Óssea/administração & dosagem , Difosfonatos/administração & dosagem , Imidazóis/administração & dosagem , Interferon-alfa/administração & dosagem , Osteólise Essencial/tratamento farmacológico , Polietilenoglicóis/administração & dosagem , Adolescente , Depsipeptídeos , Quimioterapia Combinada , Feminino , Fusarium , Humanos , Interferon alfa-2 , Osteólise Essencial/complicações , Osteólise Essencial/patologia , Derrame Pleural/tratamento farmacológico , Derrame Pleural/etiologia , Derrame Pleural/patologia , Proteínas Recombinantes , Ácido ZoledrônicoRESUMO
Transient left ventricular apical ballooning (TLVAB) is a recently proposed clinical entity that mimics an acute coronary syndrome in its clinical presentation. Retrospective studies suggest that it may account for 1% of myocardial infarction diagnoses. We provide a review of TLVAB including its clinical presentation, diagnostic studies, etiology, pathogenesis, criticism, complications, and management.
