1.
Bull Exp Biol Med
; 161(2): 218-20, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27383154
RESUMO
Single administration of the obestatin fragment 1-4 (300 nmol/kg) to male Wistar rats produced a significant weight loss in male rats on observation days 5-8, while in female rats only on day 8. In addition, males demonstrated decreased risk factor in the elevated plus-maze test, but no effect of the preparation on behavior of female rats was revealed. Obestatin fragment 1-4 had no effect on corticosterone level 1 week after single administration in both females and male rats.
Assuntos
Fármacos Antiobesidade/farmacologia , Oligopeptídeos/farmacologia , Animais , Corticosterona/sangue , Feminino , Masculino , Aprendizagem em Labirinto , Ratos Wistar , Assunção de Riscos , Estresse Psicológico/sangue
2.
Dokl Biol Sci
; 460: 1-4, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25773239