RESUMO
A phenomenon of oculosympathetic reflex (OSR) has been discovered: the activation of heart rate during an eyeball suction. The OSR seems to be due to either activation of eyeball proprioceptors mediated by the RF and locus coeruleus, or to a baroreflex mechanism originated from the intraocular portion of art. ophthalmica. The OSR and Aschner's reflex seem to trigger some vegetative barometeopathetic responses.
Assuntos
Frequência Cardíaca/fisiologia , Fenômenos Fisiológicos Oculares , Reflexo Oculocardíaco/fisiologia , Adolescente , Adulto , Eletrocardiografia , Feminino , Humanos , Masculino , Pressão , Pulso Arterial/fisiologia , VácuoRESUMO
Comparison of the rate of HLA antigens I in 81 patients with frequently occurring sympathoadrenal paroxysms (SAP) associated with vegetovascular dystonia and 113 healthy subjects revealed the increase of the number of antigen B12 carriers among the patients as compared to the healthy subjects' group. The number of antigens A9, B35 in SAP patients was elevated whereas that of B18, B38 and B40 decreased. SAP related to age-associated hormonal rearrangements were marked by antigens Cw4 and A1, the grave SAP patterns by B12, SAP without nocturnal paroxysms and the early disease onset by the lack of antigen A19. The dominant gene that determines the onset of SAP is localizes in the HLA area. It may be associated with a hypothetical gene analogous to the locus implicated in the determination of the threshold of neuromuscular excitability of rats. It is not excluded that such a relationship is mediated via the blood content of Mg2+.
Assuntos
Doenças das Glândulas Suprarrenais/imunologia , Doenças do Sistema Nervoso Autônomo/imunologia , Antígenos HLA/sangue , Sistema Nervoso Simpático , Doenças das Glândulas Suprarrenais/epidemiologia , Doenças das Glândulas Suprarrenais/genética , Adulto , Doenças do Sistema Nervoso Autônomo/epidemiologia , Doenças do Sistema Nervoso Autônomo/genética , Biomarcadores/sangue , Distribuição de Qui-Quadrado , Suscetibilidade a Doenças/epidemiologia , Suscetibilidade a Doenças/imunologia , Distonia/epidemiologia , Distonia/genética , Distonia/imunologia , Feminino , Predisposição Genética para Doença , Antígenos HLA/genética , Humanos , Masculino , SíndromeRESUMO
In 30 patients with vegetative crises (VC) (the structure of the crises met DSM-III criteria for panic attacks), the typing of histocompatibility (HLA) antigens was carried out. Antigen HLA-Cw6 was found in 53% of the patients (in 10% in controls [pc < 0.01]). The relative risk of VC in persons having antigen Cw6 is 10.3. The data obtained allow regarding antigen HLA-Cw6 as of potential genetic markers of VC.
Assuntos
Doenças do Sistema Nervoso Autônomo/genética , Transtorno de Pânico/genética , Adulto , Doenças do Sistema Nervoso Autônomo/sangue , Doenças do Sistema Nervoso Autônomo/epidemiologia , Doenças do Sistema Nervoso Autônomo/etiologia , Antígenos de Grupos Sanguíneos/genética , Distribuição de Qui-Quadrado , Feminino , Antígenos HLA/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Transtorno de Pânico/sangue , Transtorno de Pânico/epidemiologia , Transtorno de Pânico/etiologiaRESUMO
Prevalence of the vegetative dystonia syndrome (VDS) among the workers at a chemical plant increased depending on the duration of work, industrial noise being the major factor in the hazardous working conditions. The VDS risk groups were traced in the age-group beyond 40 with the duration of work over 10 years. The following techniques can be adequately used in the VDS detection: baresthesiometry , cardiointervalometry at rest and cardiointervalographic assessment of the Ashmer reflex, which facilitate determination of the specific nature and manifestations of the pathologic developments, as well as an adequate choice of their correction.
