1.
Ann Univ Mariae Curie Sklodowska Med
; 46: 59-63, 1991.
Artigo
em Polonês
| MEDLINE
| ID: mdl-1365003
RESUMO
Kidneys of the rats which had been intragastrically administered Dexamethasone (10 mg/kg), were examined. Observations were carried out after a single and twice repeated application of the preparation, as well as after 7 days of everyday administration. It was found, on the basis of histological and histochemical observations (reaction to alkaline phosphatase activity, reaction to acid phosphatase activity, PAS-method staining), that both single and twice administration of Dexamethasone do not cause the damage of the kidney parenchyma, whereas after 7 days of everyday application of the preparation irreversible changes can be observed.