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1.
J Oral Maxillofac Pathol ; 28(1): 62-69, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38800418

RESUMO

Background: Various artificial chemical agents have been evaluated over many years with respect to their antimicrobial effect in oral cavity. The gold standard for removal of plaque is usage of chlorhexidine, but it can cause alteration in taste sensation and staining of teeth. Electrolytes and oxidizing water may be useful against microbes, but its clinical application has still not been evaluated. Hence this present study was conducted to evaluate the effectiveness of the alkaline ionized water on oral microbial flora. Materials and Methods: Ten non-carious, un-restored and intact freshly extracted human teeth were collected and sectioned using a round bur. Each tooth was sectioned longitudinally in two parts and stored in closed sterile containers which was filled with alkaline ionized water (Group 1) and normal water (Group 2), respectively for 15 days. The microbial growth was analyzed prior to dipping in the solutions, 3 days, 7 days and 15 days. The pH of alkaline ionized water and normal water was evaluated using pH meter before placing teeth in different solutions. Results were analyzed using t-test and the level of significance was set at ≤ 0.05. Results: No difference in bacterial colony was observed before test and after 3 days among Group 1 and Group 2, respectively. After 7 days and 15 days, statistically significant decrease in bacterial colony count was seen among Group 1 as compared to Group 2 (P ≤ 0.05). Conclusion: It was then concluded that alkaline ionized water can be effective in reduction of oral microbial flora.

2.
Artigo em Inglês | MEDLINE | ID: mdl-37362125

RESUMO

Ever since the commencement of the COVID-19 pandemic, post-recovery complications have been in the highlights, out of which rhinocerebral mucormycosis tops the chart. The surgical management of this disease was always aggressive debridement, resection, and antifungal treatment. Oronasal communication after aggressive surgical management always leads to breathing, feeding, and cosmetic impairments. In this study, cases were managed by leaving the palatal mucosa intact after the removal of all the affected hard and soft tissues including the periosteum attached to the mucosa, to preserve the palatal mucoperiosteum and to improve the postoperative complications in patients by maintaining the oronasal separation. Prospective review of the operated case of rhinocerebral mucormycosis in 20 patients was presented. An intraoral approach for hard and soft tissue resection was employed. The palatal mucoperiosteum was salvaged in all patients. Postoperative complications like oronasal communication, ill-fitting prosthesis, and healing were evaluated. A total of 20 patients underwent maxillectomy for mucormycosis involving the maxilla and palate along with other facial bones. The palatal mucosa was preserved and used for oronasal separation. The expected complications of nasal regurgitation, crustation of the maxillary cavity, ill-fitting prosthesis, etc. were evaded due to this. The administration of Inj. liposomal amphotericin B (LiAB) postsurgically has been the backbone of this procedure.

3.
Indian J Otolaryngol Head Neck Surg ; 74(Suppl 2): 2959-2962, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34026593

RESUMO

In this era of the COVID-19 pandemic, patients with diabetes mellitus are at an increased risk of secondary infections and systemic complications. Here we are reporting 2 cases in post-covid-19 patients, who were uncontrolled type 2 diabetics and diagnosed with fungal osteomyelitis and mucormycosis respectively. Both patients were treated surgically immediately.

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