[Metabolism of collagen in patients with Dupuitren's contracture].

Results of investigation of collagen metabolism in Dupuitren's contracture (DC) were summarized. The patients were operated for calculous cholecystitis and DC stages II - III. The changes revealed witnessed about more expressed degradation of collagen and affection of the elastin components of connective tissue. On background of the pathological process progress in palmar aponeurosis in patients, suffering DC, a content of oxyproline have enhanced trustworthy in urine and reduced in tissue of a changed palmar aponeurosis.

[Hemoperitoneum as a predictor of the traumatic process complications in the injured persons with severe combined trauma].

Multifactorial analysis was conducted in 48 injured persons, who had suffered combined abdominal organs trauma, trauma severity score according to the AIS-90 scale more than 25 points, and died. There were elaborated theoretical aspects of prognostication of the injured person's death timing. There was established, that while hemoperitoneum volume enhancement by 200 ml (critical level of hemoperitoneum is considered 682 ml) the death timing becomes accelerated by 1.2 h.

[Morphological changes in hepatic tissues in patients, suffering Dupuytren's contracture and chronic hepatitis].

The results of morphological investigation of hepatic tissues in 98 patients, suffering contracture of Dupuytren, chronic hepatitis and hepatic fibrosis stages I, II i III, were adduced. The patients were operated on for calculous cholecystitis. The attempt to organize the groups with certain morphological changes, depending on the hepatic pathological process persistence (up to 5 yrs, from 5 to 10 yrs, over 10 yrs) have appeared nonfair. The changes revealed are too different and characteristic not only for the examined patients.

[Assessment of functional activity of phagocytic system in patients suffered from Dupuytren's contracture with hepatic fibrosis].

Dupuytren's contracture--a pathology that should not be seen as an isolated lesion tendon-aponeurotic structures of the palmar surface of the hand, but as a disease that requires careful research and a comprehensive, differentiated approach to treatment. The aim of the study was to investigate the functional activity of the phagocytic system of Dupuytren's contracture patients with chronic hepatitis and liver fibrosis in liquidators of the CHNPP accident consequences. The resulting study 188 patients aged 45-65 years showed the correlation of the data of the functional activity of phagocytic system with degree of liver fibrosis, thus objectively assess the patient's condition and make the appropriate correction in the diagnostic criteria as well as in medical and rehabilitative programs.

[Pathogenetic aspects of complex treatment of Dupuytren's contracture in patients with chronic hepatitis].

The results of Dupuytren's contracture treatment in patients, suffering chronic hepatitis with the hand deformity grade II and III, in the injured persons and liquidators of the Chernobyl disaster consequences, conducted in 2000-2010 yrs., were adduced. Beginning from the third week, when an active movements had emerged, the patients were treated locally, including lidase and solution, which consisted of dimexid, isotonic saline and furazolidon.

[The role of ultrasonograpy in complex diagnosis of retroperitoneal hematomas in the injured persons with multiple trauma].

Efficacy of treatment of "high-energy trauma" depends on timely establishing of diagnosis. Modern radiological diagnosis permits to reveal the damage of the abdominal parenchyma organs and kidneys, as well as retroperitoneal space hematoma. The ultrasonograhic investigation method (UIM) is considered the leading one in estimation of traumatic damage of parenchymatous organs of abdominal cavity and retroperitoneal space because of contraindications absence, as well as radiological load, noninvasiveness and accessibility. The issues of ultrasonographic diagnosis of retroperitoneal hematoms in closed abdominal trauma and lumbar region were enlighted, their echosemiotics is adduced. There were examined 65 injured persons, suffering polysystemic and polyorgan damages, in whom retroperitoneal hematoma was revealed. The UIM data were compared with intraoperative diagnosis results. There were established the method possibilities not only in the hematoms diagnosis but in dynamical control conduction for the structure changes in the damaged region in conditions of favorable course or in complications occurrence, retroperitoneal abscess in part.

[Treatment and diagnostic tactics of the injured persons with multisystem and multiorgan damages].

The treatment and diagnostic tactics efficacy in 6266 injured persons with multisystem and multiorganic affection were analyzed. The equal clinical and organization decisions depended from patient's stage was established. That whey all of this must be considered at the planning of treatment and diagnostically tactics of patients.

[Diagnostic and treatment aspects of cardiac and pericardial wounds].

Basing on experience of treatment of 97 injured persons there was analyzed the course of cardiac and pericardial wounding, the conventional and modern diagnostic possibilities were compared, the staged approach, directed to the surgical treatment results improvement, was systematized.

[Analysis of mortality of injured persons with isolated and multiple trauma]. / Analiz letal'nosti poterpilykh z izol'ovanoiu ta posdnanoiu travmoiu.

The causes of death of 192 injured persons with isolated or combined trauma were analyzed.