RESUMO
The peculiarities of the response of the sympathoadrenal system to psychoemotional and hypoxic stress in healthy young people and in aged people with physiological and accelerated aging of respiratory system were studied. It was shown that in aging a more pronounced response of the sympathoadrenal system to psychoemotional stress. At the same time, elderly people with different types of aging of the respiratory system did not demonstrate a difference in the response of the sympathoadrenal system to psychoemotional stress. Unlike in young people, in aged people, combination of psychoemotional and hypoxic stresses resulted in further activation of the sympathoadrenal system. The reaction of the sympathoadrenal system was more expressed in elderly people with accelerated ageing of the respiratory system.
Assuntos
Glândulas Suprarrenais/fisiopatologia , Senilidade Prematura/fisiopatologia , Envelhecimento/fisiologia , Hipóxia/fisiopatologia , Sistema Respiratório/fisiopatologia , Estresse Psicológico/fisiopatologia , Sistema Nervoso Simpático/fisiopatologia , Glândulas Suprarrenais/metabolismo , Adulto , Idoso , Envelhecimento/metabolismo , Envelhecimento/psicologia , Senilidade Prematura/metabolismo , Senilidade Prematura/psicologia , Catecolaminas/sangue , Coração/inervação , Frequência Cardíaca/fisiologia , Humanos , Hipóxia/metabolismo , Hipóxia/psicologia , Pessoa de Meia-Idade , Estresse Psicológico/metabolismo , Adulto JovemRESUMO
In hypertensive patients with concomitant obesity observed decrease in activity of dopaminergic system in conjunction with increased activity of the renin-angiotensin-aldosterone system. Identified changes point to the advisability of appointing this group of patients the dopamine receptor agonist - bromocriptine-KV and antagonist of aldosterone - veroshpiron. As a result of treatment was an increase in dopamine levels in the urine, a decrease of aldosterone in the blood, normalization of the daily blood pressure monitoring.