[Some aspects of the clinical course of infectious endocarditis in different age groups]. / Osobennosti klinicheskogo techeniia infektsionnogo éndokardita u bol'nykh razlichnogo vozrasta.

Differences were recordable in the course of infectious endcarditis in patients at different ages (young, middle-aged, elderly, senile, n = 85).

[Clinico-morphologic characteristics of pneumococcal meningoencephalitis]. / Kliniko-morfologicheskie osobennosti pnevmokokkovogo meningoentsefalita

A relationship between PM severity and early onset of dramatic microcirculatory disorders of the brain and viscera leading to DIC syndrome and infective toxic shock has been reported in a clinicomorphological study of 12 PM cases. Being the main PM target, the brain is afflicted more seriously. The related shock has specific features: toxicosis and brain swelling. They should be taken into consideration when performing reanimation.

[Morphology of infectious-toxic shock in salmonellosis]. / Morfologiia infektsionno-toksicheskogo shoka pri sal'monelleze.

Clinico-morphological data on a severe course of salmonellosis (Stenley Salmonella) with the development of the infectious-toxic shock are presented. The shock was manifested by changes of the microcirculatory bed with the development of disseminated intra vascular blood coagulation (DIBC), brain and lung oedema as well as degenerative and necrobiotic lesions of the inner organs (acute tubular renal necrosis, necrobiosis and necrosis of the gastrointestinal tract epithelium, necrobiotic processes in the adrenal parenchyma, neuronal lysis etc.) as a consequence of circulatory disturbances determining the severity of the course and outcome of the disease. The possibility of a protracted course of the DIBS-syndrome as the main component of the infectious-toxic shock is shown and pathogenetically grounded.

[Study of the relation between cardiac function and the tonus of resistant vessels in experimental disorder of coronary circulation]. / Issledovanie vzaimootnoshenii mezhdu funktsiei serdtsa i tonusom rezistivnykh sosudov pri eksperimental'nom narushenii koronarnogo krovoobrashcheniia

In tests set up on dogs under morphine-chloralose anesthesia features specific for upset cardio- and hemodynamics following a primary and repeated (against the background of a preliminarily provoked myocardial infarction) acute disruption of the coronary circulation were investigated. The development of an acute ischemia of the myocardium in animals with preliminarily induced chronic disruption of the coronary circulation was shown to be attended by more intensive than in healthy dogs hemodynamic shifts and functional disorders of the heart, whereas the reflex component of the reaction, the vasodilating reactions of the peripheral vessels, in particular, proved much less marked. Possible mechanisms accounting for differences in the derangement of the cardio- and hemodynamics in primary and repeated ischemia of the myocardium are discussed.