[Electromagnetic information in the phenomenon of life]. / Elektromagnitnaia informatsiia v iavlenii zhizni.

The author's original experiments and ideas have been summarized, which concern the role of natural background radiation in maintenance of electromagnetic information essential for existence of the living organism as an integral whole.

[Secondary biogenic radiation of human body]. / Vtorichnoe biogennoe izluchenie chelovecheskogo organizma.

It was shown that tissues of alive healthy hyman organism (hands, surface of breast, hair) permanently emitted secondary biogenous radiation (SBR), which was registered with biological detectors. The hypothesis was suggested that natural background radiation permanently excited biopolymers (proteins, nucleic acids) in condensed state and induced electromagnetic field of SBR which is vitally important for human organism. The field partly extends beyond the organism, where it is registered with sensitive biological detectors.

[Secondary biogenic radiation of gamma-irradiated human blood]. / Vtorichnoe biogennoe izluchenie gamma-obluchennoi krovi cheloveka.

The samples of blood freshly taken from healthy men were gamma-irradiated with a dose of 10 Gy. It was shown that after the treatment the blood gained the capacity to emit secondary biogenic radiation. Emission lasted for some hours, passed through quartz-glass cuvette and was revealed by stimulating influence on biological detector (sprouting seeds).

[The effect of low doses of a synthetic analog of a quinoid radiotoxin on the viability of normal and gamma-irradiated animals]. / Vliianie malykh doz sinteticheskogo analoga khinoidnogo radiotoksina na zhiznesposobnost' normal'nykh i gamma-obluchennykh zhivotnykh.

The method for a production of synthetic quinoid radiotoxins in vitro has been developed and described. Synthetic quinoid radiotoxins like quinoid radiotoxins (qRT) which are being produced from irradiated tissues of the organisms have demonstrated high toxicity at relatively high qRT concentrations. However, when synthetic qRT is introduced into the organisms in ultra-small concentrations, one can observe the opposite action: the resistance of the organism increases and a number of essential functions are activated. Quinoid radiotoxins are assumed to take part in regulatory processes responsible for radiation hormesis.

[Native protein activated by low doses of gamma radiation as a source of secondary biogenic radiation]. / Nativnyi belok, vozbuzhdennyi gamma-radiatsiei v malykh dozakh, kak istochnik vtorichnykh biogennykh izluchenii.

If is demonstrated that native protein of egg-white after being gamma-irradiated with law doses is able to stimulate transition of cells of remote biological detector from non-cycling state to proliferation even if irradiated protein is separated from detector by quartz-glass. Animal tissues which have a high protein content (freshly cut hair; insect bodies) reveal the same ability. The role of natural background radiation in the maintenance of energy excitation, state of living tissue proteins is discussed.

[Possible mechanisms of the participation of natural radiation background in the stimulation of cell division]. / Vozmozhnye mekhanizmy uchastiia prirodnogo radiatsionnogo fona (PRF) v stimuliatsii deleniia kletok.

Suggested is a new conception about participation of natural environmental radiation in stimulation development of cells. According this conception atomic radiation, in low doses, transfer DNA in excited state with formation polaritons, with long time give coherent radiation likeness mitogenic rays discover by A. G. Gurwitsch.

[The significance of the radioactive isotope potassium-40 for the normal development of the animal organism]. / Znachenie radioaktivnogo izotopa kaliia-40 dlia normal'nogo razvitiia zhivotnogo organizma.

21-day-old rats subjected to nourishing by KCl (20-30 mg per day) without radioactive isotope 40K. Besides the decrease of 40K content in animal tissue (30-50%) a reducing of body weight was obtained. In the second set of experiments in the lead (9 cm thick) chamber with low (20 times) background radiation the trustworthy decrease of young mouse development was observed under the simultaneous reducing other components of background radiation (radon, products of its disintegration, gamma, beta radiation, cosmic radiation). Possible mechanisms of necessity of 40K natural concentration for the normal development of the animal organism are discussed.

[The key mechanisms of radiation hormesis]. / Vedushchie mekhanizmy radiatsionnogo gormezisa.

The different cellular responses to high (suppressive) and low (stimulant) doses of atomic radiation suggest understanding of radiation hormesis, since the well developed mechanisms of damaging effect of atomic radiation (radiodamage of DNA, chromosomal aberrations, death of radiosensitive cells) cannot explain the converse effects of low stimulant radiation doses. Here the direct or indirect excitation of membrane receptors comes to the foreground. The excitation activates membrane-bound enzymes which control many vitally important processes. Now that an increasing proportion of the general population is exposed to low chronic doses of ionizing radiation, the knowledge of radiation hormesis acquires great importance, particularly, for temporal predictions of its consequences. Although this problem is far from complete understanding, it is, undoubtedly, wrong to estimate the hazard of the low radiation doses by straight extrapolation of the data obtained with much higher doses and during shorter time periods.

[The effect of beta-carotene on the cytoplasmic membrane lipids of cells in rats under chronic gamma irradiation]. / Vliianie beta-karotina na lipidy tsitoplazmaticheskikh membran kletok krys pri khronicheskom gamma-obluchenii.

Chronic gamma irradiation of rats at a dose rate of 12.9 rad/day for 155 days (total dose 20 Gy) did not change the cholesterol level in the brush border membrane of the small intestine. Maintenance of rats on a beta-carotene-enriched diet (daily throughout the irradiation period, at a diurnal dose of 3 mg/kg body weight produced an increase in cholesterol levels in the small intestinal brush border membranes. The phospholipid level after gamma irradiation alone did not change, but it was increased in gamma-irradiated rats fed with carotene, this increase being most pronounced for sphingomyelin. Beta-carotene decreased the cholesterol/phospholipid ratio in the brush border membrane of irradiated rats. Activation of lipid synthesis (as seen from inclusion of 2-14C-acetate in the epitheliocyte lipids of irradiated animals) and no influence of beta-carotene on the inclusion of the label in small intestine epitheliocytes of irradiated animals have been revealed. In the presynaptic membranes of brain nerve endings, chronic gamma irradiation of animals produced a deep fall of cholesterol and phospholipid levels. Also, a tendency was revealed for stimulation of transport of the neurotransmitter amino acids GABA and L-glutamate across the presynaptic membranes of nerve endings. Beta-carotene normalized the phospholipid and cholesterol levels in brain presynaptic membranes of irradiated rats, as well as decreased L-glutamate transport. It is assumed that the modifying and normalizing effects of beta-carotene on the lipid exchange of plasma membranes upon chronic irradiation of animals and permanent introduction of the drug are associated with the radioprotector activity of beta-carotene.

[The display of hormesis in the action of quinoid radiotoxins]. / Proiavlenie gormezisa v deistvii khinoidnykh radiotoksinov.

Two hours before irradiation (7.5 Gy) mice were injected with quinoid radiotoxins in concentrations close to those formed in mouse blood after gamma-irradiation with a dose of 10 cGy. This increased the survival rate (from 10-20% to 80%), prevented the radiation-induced weight loss, and increased catalase activity in the liver and blood of exposed animals.

[Effects of chronic gamma irradiation on the activity of adenylate cyclase in rat lung tissue]. / Vliianiie khronicheskogo gama-oblucheniia na aktivnost' adenilattsiklazy legochnoi tkani krys.

Different phase changes were observed in adenylate cyclase (AC) activity of pulmonary tissue plasma membranes under chronic gamma-irradiation of rats at a dose-rate of 12.9 cGy/day. Comparison of AC basal activity with the data reported earlier on changes in ornithine decarboxylase activity under similar radiation conditions showed unidirectional changes which indicated that cAMP-dependent processes were possibly involved in radiation modification of ornithine decarboxylase.