RESUMO
Out of the total number of 2455 individuals who had passed a primary screening, a group of men aged 45--59 years, with average (borderline) values of arterial pressure (AP), serum cholesterol (CH), and glucose levels after the glucose load, was selected for studies of potential lowering of the level of risk factors of ischaemic heart prevention. The enrollment of the probands lasted 9.4 months on the average (+/- 6.0 months); the preventive double-blind study proper lasted 12 months. The levels of the three specified risk factors sank both during the enrollment period and during the proper 1-year preventive therapy period. The risk factor levels were substantially lowered both in consequence of repetitive regular examinations and by the action of drug treatment (this applies especially to the CH level). In the evaluation of the results of the preventive study, therefore, also the effects of the lowering of the AP and of the CH and glucose levels even to the average values have to be taken into account. The results of the preventive study confirm that it is possible to lower the risk of IHD among the population.
