Identifying task-relevant spectral signatures of perceptual categorization in the human cortex.

Human brain has developed mechanisms to efficiently decode sensory information according to perceptual categories of high prevalence in the environment, such as faces, symbols, objects. Neural activity produced within localized brain networks has been associated with the process that integrates both sensory bottom-up and cognitive top-down information processing. Yet, how specifically the different types and components of neural responses reflect the local networks' selectivity for categorical information processing is still unknown. In this work we train Random Forest classification models to decode eight perceptual categories from broad spectrum of human intracranial signals (4-150 Hz, 100 subjects) obtained during a visual perception task. We then analyze which of the spectral features the algorithm deemed relevant to the perceptual decoding and gain the insights into which parts of the recorded activity are actually characteristic of the visual categorization process in the human brain. We show that network selectivity for a single or multiple categories in sensory and non-sensory cortices is related to specific patterns of power increases and decreases in both low (4-50 Hz) and high (50-150 Hz) frequency bands. By focusing on task-relevant neural activity and separating it into dissociated anatomical and spectrotemporal groups we uncover spectral signatures that characterize neural mechanisms of visual category perception in human brain that have not yet been reported in the literature.

Mental state space visualization for interactive modeling of personalized BCI control strategies.

OBJECTIVE: Numerous studies in the area of BCI are focused on the search for a better experimental paradigm-a set of mental actions that a user can evoke consistently and a machine can discriminate reliably. Examples of such mental activities are motor imagery, mental computations, etc. We propose a technique that instead allows the user to try different mental actions in the search for the ones that will work best. APPROACH: The system is based on a modification of the self-organizing map (SOM) algorithm and enables interactive communication between the user and the learning system through a visualization of user's mental state space. During the interaction with the system the user converges on the paradigm that is most efficient and intuitive for that particular user. MAIN RESULTS: Results of the two experiments, one allowing muscular activity, another permitting mental activity only, demonstrate soundness of the proposed method and offer preliminary validation of the performance improvement over the traditional closed-loop feedback approach. SIGNIFICANCE: The proposed method allows a user to visually explore their mental state space in real time, opening new opportunities for scientific inquiry. The application of this method to the area of brain-computer interfaces enables more efficient search for the mental states that will allow a user to reliably control a BCI system.

Direct information transfer rate optimisation for SSVEP-based BCI.

OBJECTIVE: In this work, a classification method for steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) is proposed. The method is based on information transfer rate (ITR) maximisation. APPROACH: The proposed classification method uses features extracted by traditional SSVEP-based BCI methods and finds optimal discrimination thresholds for each feature to classify the targets. Optimising the thresholds is formalised as a maximisation task of a performance measure of BCIs called information transfer rate. However, instead of the standard method of calculating ITR, which makes certain assumptions about the data, a more general formula is derived to avoid incorrect ITR calculation when the standard assumptions are not met. MAIN RESULTS: The proposed method shows good performance in classifying targets of a BCI, outperforming previously reported results on the same dataset by a factor of 2 in terms of ITR. The highest achieved ITR on the used dataset was 62 bit min-1. SIGNIFICANCE: This approach allows the optimal discrimination thresholds to be automatically calculated and thus eliminates the need for manual parameter selection or performing computationally expensive grid searches. The proposed method also provides a way to reduce false classifications, which is important in real-world applications.

Activations of deep convolutional neural networks are aligned with gamma band activity of human visual cortex.

Recent advances in the field of artificial intelligence have revealed principles about neural processing, in particular about vision. Previous work demonstrated a direct correspondence between the hierarchy of the human visual areas and layers of deep convolutional neural networks (DCNN) trained on visual object recognition. We use DCNN to investigate which frequency bands correlate with feature transformations of increasing complexity along the ventral visual pathway. By capitalizing on intracranial depth recordings from 100 patients we assess the alignment between the DCNN and signals at different frequency bands. We find that gamma activity (30-70 Hz) matches the increasing complexity of visual feature representations in DCNN. These findings show that the activity of the DCNN captures the essential characteristics of biological object recognition not only in space and time, but also in the frequency domain. These results demonstrate the potential that artificial intelligence algorithms have in advancing our understanding of the brain.

Multiagent cooperation and competition with deep reinforcement learning.

Evolution of cooperation and competition can appear when multiple adaptive agents share a biological, social, or technological niche. In the present work we study how cooperation and competition emerge between autonomous agents that learn by reinforcement while using only their raw visual input as the state representation. In particular, we extend the Deep Q-Learning framework to multiagent environments to investigate the interaction between two learning agents in the well-known video game Pong. By manipulating the classical rewarding scheme of Pong we show how competitive and collaborative behaviors emerge. We also describe the progression from competitive to collaborative behavior when the incentive to cooperate is increased. Finally we show how learning by playing against another adaptive agent, instead of against a hard-wired algorithm, results in more robust strategies. The present work shows that Deep Q-Networks can become a useful tool for studying decentralized learning of multiagent systems coping with high-dimensional environments.