[The depression of the reproduction of the human immunodeficiency virus by the use of Bogomolets antireticular cytotoxic serum]. / Pryhnichennia reproduktsiï virusu imunodefitsytu liudyny za dopomohoiu antyretykuliarnoï tsytotoksychnoï syrovatky Bohomol'tsia.

The action of the Bogomolets' antireticular cytotoxic serum (ACS) as a HIV-1 reproduction inhibitor was studied on the model of human lymphoblastoid cell line MT-4/BRU (acute infection). The HIV-1 reproduction inhibition was estimated according to cell protection level for virus cytopathic action and p24 antigen level in the cultural media. The both tests data on ACS usage in dilutions 1:160-1:640 prove that the virus inhibition effect which may be compared with anti-HIV action of the well-known agent, azidothymidine, was observed. At this dilutions range ACS is devoid of the cell toxicity. The conclusion about perspectivity of ACS usage in the AIDS complex therapy was drawn.