RESUMO
Chlamydia trachomatis is one of the main etiologic agents in pelvic inflammatory disease (PID) in Oslo. Up to two thirds of the 65 PID cases studied were associated with a chlamydial infection. The incidence of cervical gonorrhea was low (7.7%). Anaerobic bacteria were not isolated from the fallopian tubes or peritoneal fluid of any of the patients. Chlamydia-associated PID is characterized by a protracted course and vague symptoms. The laparoscopic findings indicate more severe inflammatory changes of the tubes than in patients in whom these agents were not found. The highest incidence of chlamydia-associated PID occurred in younger subjects, among whom the intrauterine contraceptive device was more frequently used. Perihepatitis was diagnosed in PID patients with and without chlamydial infection of the genital tract.
Assuntos
Infecções por Chlamydia , Doença Inflamatória Pélvica/etiologia , Adolescente , Adulto , Fatores Etários , Líquido Ascítico/microbiologia , Infecções por Chlamydia/microbiologia , Chlamydia trachomatis/isolamento & purificação , Tubas Uterinas/microbiologia , Feminino , Hepatite/etiologia , Humanos , Imunoglobulinas/análise , Neisseria gonorrhoeae/isolamento & purificação , Doença Inflamatória Pélvica/microbiologiaRESUMO
Of four cases of acute salpingitis and perihepatitis confirmed by laparoscopy Chlamydia trachomatis was cultured from the cervix only in two and from both the cervix uteri and the Fallopian tubes in two; the latter finding has not been reported from cases with combined salpingitis and perihepatitis (Fitz-Hugh-Curtis syndrome). Since gonococci, other aerobic, or anaerobic bacteria were not isolated from the Fallopian tubes, an aetiological relationship between C trachomatis and the Fitz-Hugh-Curtis syndrome is suggested.
Assuntos
Infecções por Chlamydia , Hepatite/etiologia , Doença Inflamatória Pélvica/etiologia , Peritonite/etiologia , Doença Aguda , Adolescente , Adulto , Colo do Útero/microbiologia , Chlamydia trachomatis/isolamento & purificação , Tubas Uterinas/microbiologia , Feminino , Humanos , SíndromeRESUMO
The efficacy of pivampicillin, administered in a dose of 350 mg three times daily or 500 mg twice daily, was compared in 107 patients with acute salpingitis. Both regimens were equally effective. Fortyseven out of 56 patients given the 500 mg doses were cured and four improved. Of the patients who received the 350 mg doses, 46 out of 51 were cured and three improved. Patients were divided into two groups with severe and mild infections respectively. The 500 mg dose of pivampicillin was significantly more effective in reducing pyrexia in all patients including those with severe infections. Mean treatment duration was shorter in patients with severe infections given 500 mg of pivampicillin twice daily (11.4 days) than in those receiving 350 mg three times daily (14.5 days). Slight gastrointestinal discomfort occurred in 9% of patients receiving the 500 mg dose and in 4% of those receiving the 350 mg dose. The overall incidence of exanthema was about 5%. The twice daily regimen of 500 mg pivampicillin is recommended since it is more practical for the departments concerned and patient compliance is better.
