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Eksp Klin Gastroenterol ; (1): 30-4, 2014.
Artigo em Russo | MEDLINE | ID: mdl-25518453

RESUMO

In present work we studied the morphological features of the esophageal mucosa in 63 children with gastroesophageal reflux disease (GERD). The biopsies were taken at level of 3 cm above a Z-line and at level of 0.5-1 cm above a Z-line. The results of our study showed that the mucosa of the esophago-gastric junction may contain areas covered with columnar epithelium of 44.4% of children in the biopsies from the level of 0.5-1.0 cm above the Z-line. Inflammatory changes in the mucosa of the esophago-gastric junction identified in 71.4% of cases. The inflammation in the majority of cases (82.1%) was observed in the presence of H. pylori infection (p < 0.001). In addition, H. pylori in our study, we noted the relationship detection carditis in overweight child. When compared with the height-weight parameters, the excess body weight was observed in 17 of 28 patients. We couldn't found increasing detection of the cardia in patients with erosive GERD compared with non-erosive variants.


Assuntos
Junção Esofagogástrica/patologia , Mucosa Gástrica/patologia , Refluxo Gastroesofágico/patologia , Infecções por Helicobacter/patologia , Sobrepeso/patologia , Adolescente , Biópsia , Criança , Endoscopia do Sistema Digestório , Junção Esofagogástrica/microbiologia , Mucosa Gástrica/microbiologia , Refluxo Gastroesofágico/complicações , Refluxo Gastroesofágico/microbiologia , Infecções por Helicobacter/complicações , Infecções por Helicobacter/microbiologia , Helicobacter pylori/isolamento & purificação , Humanos , Sobrepeso/complicações , Sobrepeso/microbiologia
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