[Histological characteristics of the reactions of cerebral neuroglia in laboratory animals]. / Gistologicheskaia kharakteristika reaktsii neiroglii golovnogo mozga laboratornykh zhivotnykh.

Literature data and the authors' results, concerning structural and functional peculiarities of all varieties of the cerebral neuroglia under effect of a cranial-cerebral trauma, neurotropic chemical products and oxygen insufficiency have been considered. Ideas that neuroglial reactions under the conditions mentioned are proved to be constant and in dependence of certain peculiarities of each case are either progressive or regressive. The reaction degree is mainly proportional to the disturbance power. Nevertheless, certain discrepancies (ariactivity including) can be observed; this is also determined by a combination of prerequisites and by a peculiarity of individual reactivity of the CNS. The greatest stability of astroglia has been stated. Possible variations in relation between changes of neurons and gliocytes are mentioned. Suggestions are made that diffuse-focal progressive reactions of macroglia under conditions of neurotoxicoses can be determined not by proliferation of cells, but by their migration.

[Modern concepts of neurotoxicity]. / Sovremennye predstavleniia o neirotoksichnosti.

A systematic analysis of the main literature published in the recent five years which reflects a variety of aspects of research on specifics of the nervous system reactions in humans and animals to effects of neurotropic chemical products was performed. The further insight into the essence of neurotoxicity would contribute to the development of necessary measures for prevention and therapy of exogenous neurointoxications.

[Reactions of cellular structures of the brain of laboratory animals in oxygen deficiency]. / Reaktsii kletochnykh struktur golovnogo mozga laboratornykh zhivotnykh na kislorodnuiu nedostatochnost'.

Analysis of the latest literature data and the authors' neuromorphological observations give the possibility to consider that structural reactions of the cerebral cellular elements of higher animals to oxygen insufficiency have a common base, but vary in dependence of the hypoxia form and the character of its influence and peculiarities of individual reactivity of the organism. Neurons and gliocytes possess rather effective mechanisms of resistance to hypoxia and ischemia, and are connected with intracellular regenerative and adaptive-compensatory processes. Hypoxic factor of pathogenesis of dystrophic-destructive changes in the cerebral cells is, however, subcoordinative, but not self-sufficing in all cases without any exception. Hypoxic and intoxicational lesions of the brain may have an independent cytological expression, despite the fact that differentiation of the combined signs is usually difficult.

[Structural characteristics of the "dark" cells of animal and human brains]. / O strukturnykh osobennostiakh "temnykh" kletok golovnogo mozga zhivotnykh i cheloveka.

An analysis of contradictory data from literature and the authors' observations (light- and electron-microscopic examination of various pathological and experimental material) permits confirming the validity of the conclusion that "dark" cells of the animal and human nervous tissue represent in most cases elements arising during development and are functionally dependent.

[Current concepts on the "dark" cells of human and animal brains]. / Sovremennye predstavleniia o "temnykh" kletkakh golovnogo mozga zhivotnykh i cheloveka.

The latest current literature is reviewed on the dark cells of the brain and internal organs of animals and man. The following questions are considered: shrinked and picnomorphic neurons; dark neurons and glyocytes--structure and function; and perspectives of research into the problem of dark cells. A conclusion has been made that in most cases dark cells of the animal and human nervous tissue constitute functionally conditioned elements emerging during the life span.