RESUMO
Nosocomial infections are often induced by the presence of pathogenic organisms on the surface of medical devices or hospital equipment. Chemical modifications of the surface are recognized as efficient strategies to prevent bacterial adhesion but they may have a negative impact on the material's interaction with living tissues. Here we have developed a photoactivated method for the modification of titanium substrates. A photoinduced technique employing a grafting-onto process has been successfully performed to covalently anchor an imidazolium-derivative siloxane onto titanium surfaces. Imidazolium surfaces showed higher bacteria-repellency performances than native titanium substrates, achieving more than 98% anti-adhesion efficiency against Escherichia coli after 24 h of incubation. In addition, these surfaces allowed for the adhesion and viability of osteoblasts cells without evidence of cytotoxicity.
Assuntos
Aderência Bacteriana , Materiais Revestidos Biocompatíveis/química , Escherichia coli/citologia , Imidazóis/química , Siloxanas/química , Titânio/química , Células 3T3 , Animais , Linhagem Celular , Infecções por Escherichia coli/prevenção & controle , Humanos , Hidrólise , Camundongos , Processos Fotoquímicos , Infecções Estafilocócicas/prevenção & controle , Staphylococcus aureus/citologia , Propriedades de SuperfícieRESUMO
We report a pseudotumour in the urinary bladder following total hip replacement with review of the literature. Pseudotumour in the urinary bladder as a late complication of total hip replacement is an extremely rare condition. In this case, cross-sectional imaging modalities including sonography, CT and MR showed a hypervascular polypoid mass in the urinary bladder and adjacent wall thickening with a band connecting between the mass and the acetabulum. Histopathological diagnosis confirmed acute and chronic inflammation with calcification.
