[Response of the pro- and antioxidant systems to plasmapheresis in patients with advanced atherosclerosis obliterans of the legs]. / Reaktsiia pro- i antioksidantnykh sistem na provedenie plazmafereza u bol'nykh obliteriruiushchim aterosklerozom sosudov nizhnikh konechnostei pozdnikh stadii.

The effects of fractional apparatus plasmapheresis in a volume of 25% of circulating blood plasma on the processes of lipid peroxidation and on the antioxidant defence system parameters were studied in 31 patients with ischemia of the lower limbs, stage III-IV. It has been shown that plasmapheresis induces elevation of ceruloplasmin activity and superoxide dismutase activity of blood plasma, lowers the ratio of lipid oxidation to lipid peroxidation products simultaneously with intensification of lipid peroxidation that leads to regeneration of biological membranes of the body.

[The role of lipid peroxidation processes in the development of complications following reconstructive surgery on the vessels of the lower extremities]. / Rol' protsessov perekisnogo okisleniia lipidov v razvitii oslozhnenii posle rekonstruktivnykh operatsii na sosudakh nizhnikh konechnostei.

Reconstructive surgery on the vessels of the lower extremities accompanied by ischemia and the following tissue oxygenation leads to the activation of lipid peroxidation causing the destruction of cellular membranes and formation of toxic products, namely medium mass oligopeptides. The accumulation of lipid peroxidation metabolites in the blood correlates with the onset of renal-hepatic failure complicating the postoperative period.