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2.
Artigo em Inglês | MEDLINE | ID: mdl-23754871

RESUMO

The facial skin tone of two groups of Chinese women from Shanghai was compared using standard colorimetric space techniques during a 6-month interval between January and July 2011. During the study period, one group of women (n = 40) applied a potent sun-protective cosmetic product daily, while the other group (n = 40) did not use any sun protection. The results, based on images taken using a standardized digital camera coupled to a spectroradiometer, showed that sun protection largely mitigated changes in the components of skin tone, ie, lightness, melanization, and individual typology angle parameters. The skin darkening process appeared to be reduced or prevented in the sun-protected group when compared with the control group. The sun-protected women had participated in an earlier study in 2008, which confirmed that seasonal skin darkening occurs from winter through summer in Shanghaiese women. Comparing the data obtained in the winters of 2008 and 2011, we were able to identify better the impact of 3 years of aging on the components of skin tone. Comparing data between seasons on the same women with (2011 study) and without (2008 study) sun protection highlights the role of the test product in preventing skin darkening.

3.
Contact Dermatitis ; 54(5): 249-53, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16689808

RESUMO

Silicon image sensor (SIS) technology was recently introduced as an innovative tool (SkinChip, L'Oréal) providing sensitive imaging of the skin capacitance. This method can detect discrete focal variations in skin surface hydration, and thus early discrete manifestations of skin irritation induced by surfactants. In the present in vivo study, 2 neat and diluted shampoos, and 5% and 10% sodium laurylsulfate solutions were tested on human skin. Each surfactant solution was gently rubbed on the skin using wet hair wicks mimicking the casual use of a shampoo on the scalp. Clinical and SIS evaluations were carried out. In addition, the same products were tested using the ex vivo corneosurfametry bioassay performed on human stratum corneum (SC) harvested by cyanoacrylate skin surface strippings. The colourimetric index of mildness (CIM) was measured on these samples. The product reactivity with the SC was recognized by darker skin capacitance images, and by both lowered SkinChip-generated values and lowered CIM values. The extent in changes varied according to the nature of the test products and their concentrations. The SkinChip image changes likely corresponded to the acute surfactant-induced water swelling of the corneocytes. Skin capacitance imaging and corneosurfametry allow to disclose discrete surfactant-induced alterations of corneocytes.


Assuntos
Dermatite Alérgica de Contato/diagnóstico , Testes Cutâneos/instrumentação , Pele/efeitos dos fármacos , Tensoativos/farmacologia , Perda Insensível de Água/efeitos dos fármacos , Dermatite Alérgica de Contato/etiologia , Dermatite Alérgica de Contato/fisiopatologia , Método Duplo-Cego , Capacitância Elétrica , Preparações para Cabelo/efeitos adversos , Preparações para Cabelo/farmacologia , Humanos , Fenômenos Fisiológicos da Pele/efeitos dos fármacos , Testes Cutâneos/métodos , Dodecilsulfato de Sódio/farmacologia , Tensoativos/efeitos adversos
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