RESUMO
No disponible
Assuntos
Humanos , Masculino , Idoso , Insuficiência Cardíaca/tratamento farmacológico , Diuréticos/farmacocinética , Injúria Renal Aguda/fisiopatologia , Débito CardíacoRESUMO
No disponible
Assuntos
Humanos , Masculino , Adulto , Acidose Tubular Renal/complicações , Perda Auditiva Neurossensorial/complicações , Pacientes Desistentes do Tratamento , Nefrolitíase/complicações , Paralisia Periódica Hipopotassêmica/etiologiaRESUMO
No disponible
No disponible
Assuntos
Masculino , Adulto , Humanos , Pancreatite Necrosante Aguda/complicações , Injúria Renal Aguda/complicações , Amilases/sangueRESUMO
BACKGROUND: Diabetes mellitus appearing after transplant (PTDM) has generally been attributed to immunosuppressive treatment. However, the findings of several studies suggest a possible relationship between hepatitis C virus (HCV) infection and diabetes mellitus, both in the general population and in liver or kidney transplant patients. METHODS: We reviewed data corresponding to 325 kidney transplant patients who did not have diabetes before transplant and were treated with ciclosporin A posttransplant. We explored whether factors such as age, gender, weight, renal disease, immunosuppression, rejection episodes or HCV could be independent risk factors for PTDM. RESULTS: Ninety four of the 325 patients were HCV positive and 231 were HCV negative. PTDM was observed in 22.3% of the HCV positive patients versus 6.5% of the HCV negative patients (p < 0.001). The independent factors found by multivariate analysis to be predictive of PTDM were: HCV positivity (OR: 5.65, IC 95%: 2.6-12), body mass index (OR: 1,10, IC 95%: 1.02-1.2) and age (OR: 1.07, IC 95%: 1.03-1.12). CONCLUSIONS: Our findings support a link between HCV and PTDM.
Assuntos
Ciclosporina/efeitos adversos , Diabetes Mellitus/epidemiologia , Hepatite C/complicações , Hepatite C/epidemiologia , Imunossupressores/efeitos adversos , Transplante de Rim , Adulto , Ciclosporina/administração & dosagem , Diabetes Mellitus/diagnóstico , Feminino , Sobrevivência de Enxerto , Hepacivirus/imunologia , Hepacivirus/isolamento & purificação , Hepatite C/imunologia , Anticorpos Anti-Hepatite C/sangue , Humanos , Imunossupressores/administração & dosagem , Incidência , Masculino , Análise Multivariada , Razão de Chances , Complicações Pós-Operatórias , Prevalência , Estudos RetrospectivosRESUMO
We present a 45-year-old patient on chronic hemodialysis who suffered aortic endocarditis by Staphylococcus haemolyticus after bacteremia associated with a venous catheter, which was used temporarily during the maturing phase of a Cimino-Brescia arteriovenous fistula in the left forearm. Three weeks after starting antibiotic therapy, the patient suffered a septic pulmonary embolism. The catheter had been removed 4 weeks before the embolism. Thrombophlebitis of lower limbs, infection or thrombosis of the vascular access, and the involvement of right-sided cardiac structures were all discarded. We assumed that the pulmonary episode was probably a consequence of the paradoxical passage of embolic material, detached from the aortic valve, from arterial to venous circulation through the arteriovenous fistula.
