1.
Biotechnology (N Y)
; 9(10): 976-81, 1991 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1368725
RESUMO
We have increased the production of bovine chymosin in Aspergillus niger var. awamori to more than one gram per liter of secreted authentic enzyme by combining a mutagenesis protocol with a novel robotic screening program. Analysis of the superior chymosin producing strains indicated that they have enhanced capabilities to secrete extracellular proteins.