Criptococosis cutánea primaria en paciente inmunocompetente.

La criptococosis cutánea es una micosis propia de pacientes inmunodeprimidos, sobre todo aquellos con infección por el virusde la inmunodeficiencia humana (VIH). Sin embargo, existen casos infrecuentes de criptococosis cutánea en pacientes inmunocompetentes, que suelen simular otras dermatosis, lo que retrasa su diagnóstico y tratamiento. Presentamos el caso de un varón pluripatológico de 79 años, con úlceras dolorosas en dorso de mano derecha que no respondían a tratamientos tópicos. A través del estudio histopatológico y micológico se alcanzó el diagnóstico de criptococosis cutánea primaria, lográndose la remisión de las lesiones tras 6 meses de tratamiento con fluconazol.

Tolerability and effectiveness of liquid nitrogen spray cryotherapy with very short freeze times in the treatment of xanthelasma palpebrarum.

Xanthelasma are cholesterol-filled, soft, yellow plaques that usually appear on the medial aspects of the eyelids bilaterally. They are always benign lesions so therapy is usually undertaken only for cosmetic reasons. Surgical excision, chemical peeling with tricholoroacetic acid, and laser ablation are commonly used treatments. Liquid nitrogen cryotherapy is a potentially effective but rarely used treatment due to the risk of intense eyelid swelling. We report on our experience with four of our patients, and propose an explanation for the effectiveness of gentle liquid nitrogen spray cryotherapy in xanthelasma. We consider that gentle liquid nitrogen cryotherapy should be used in the treatment of xanthelasma due to the ease of application and low risk of adverse effects.

Prevalence of milia and palatal and gingival cysts in Spanish newborns.

We performed a descriptive survey of 1,000 consecutive newborns cared for in the first 3 days of life in the health area of Ferrol (in northwest Spain) to assess the prevalence and most-frequent locations of oral cysts and milia and to study the influence of different maternal and neonatal parameters in the development of these lesions. Prevalence of palatal, gingival, and cutaneous cysts was 53.7%, 13.4%, and 16.6%, respectively. Milia were predominantly located on the cheeks, chin, and forehead. We found a frequent association between palatal and gingival cysts but not between oral cysts and milia. Neonatal factors such as sex, weight at birth, and gestational age can significantly influence the development of palatal and gingival cysts.

Prospective study of erythema toxicum neonatorum: epidemiology and predisposing factors.

We performed a prospective study of 1,000 neonates investigated in the first 72 hours of life in the health area of Ferrol (northwest of Spain) to assess the prevalence of erythema toxicum neonatorum, the anatomical sites most frequently involved, the influence of different maternal and neonatal parameters, day of life of medical examination, and type of delivery (vaginal or Cesarean). Overall prevalence of erythema toxicum neonatorum was 16.7%. Lesions most frequently involved the trunk, buttocks, and proximal areas of limbs. A higher prevalence of this dermatosis was found in Caucasian newborns (p = 0.01) and those with higher birthweight (p < 0.05), greater gestational age (p < 0.05), vaginal delivery (p < 0.05), maternal age of <30 years (p = 0.28), and fewer than two previous pregnancies (p = 0.12).

Ischemic onycholysis of the hands.

Onycholysis is the distal and/or lateral separation of the nail from the nail bed. Although it can be idiopathic, there are several factors associated with the development of this condition. Ischemia is recognized as one of the possible causes, but this relationship has been poorly described in the literature. We report a case of onycholysis with a striking clinical picture and discuss the role of ischemia in the development of the lesions.

[Cryoglobulinemic syndrome: presentation of four cases with skin involvement]. / Síndrome crioglobulinémico: presentación de cuatro casos con afectación cutánea.

Cryoglobulins are serum immunoglobulins that precipitate reversibly when the serum is cooled below 371 degrees C. In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate, chronic disease consisting of palpable purpura, arthralgia and fatigue. Skin involvement is especially useful in aiding early recognition of this entity. We present four patients with cryoglobulinemic syndrome and skin lesions, in whom it was not possible to find an etiological or associated factor. We discuss the etiopathogenesis, clinical and pathological findings, treatment and prognosis of this entity.

Síndrome crioglobulinémico: presentación de cuatro casos con afectación cutánea / Cryoglobulinemic syndrome: presentation of four cases with skin involvement

Las crioglobulinas son inmunoglobulinas séricas que tienen la propiedad de precipitar de forma reversible cuando el suero es enfriado por debajo de los 37 °C. En el síndrome crioglobulinémico se pueden afectar multitud de órganos pero muchos de los pacientes sufren una enfermedad moderada y crónica consistente en púrpura palpable, artralgias y fatiga. La afectación cutánea es de especial utilidad ya que puede ayudar al reconocimiento precoz de esta entidad. Presentamos 4 pacientes con síndrome crioglobulinémico y lesiones cutáneas en los cuales no fue posible encontrar un factor etiológico o asociado. Se discute la etiopatogenia, los hallazgos clinicopatológicos, tratamiento y pronóstico de esta entidad

Cryoglobulins are serum immunoglobulins that precipitate reversibly when the serum is cooled below 371ºC. In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate , chronic disease consisting of palpable purpura, arthralgia and fatigue. Skin involvement is especially useful in aiding early recognition of this entity. We present four patients with cryoglobulinemic syndrome and skin lesions, in whom it was not possible to find an etiological or associated factor. We discuss the etiopathogenesis, clinical and pathological findings, treatment and prognosis of this entity (AU)

Carcinoma de mama en varón / Male breast carcinoma

No disponible

Tumor en la espalda / No disponible

No disponible

Liquen estriado múltiple unilateral en un adulto / Multiple unilateral lichen striatus in an adult

No disponible

No disponible

Hidroadenoma poroide / Poroid hidradenoma

El hidroadenoma poroide es una variante de poroma ecrino descrita recientemente. Esta neoplasia presenta hallazgos estructurales de hidroadenoma (áreas sólidas y quísticas) y características citológicas de los poromas (células poroides y cuticulares, estas últimas con diferenciación ductal). Se presenta el caso de un hidroadenoma poroide en una mujer de 74 años de edad, que consultó por una lesión nodular en la nalga izquierda

Poroid hidradenoma is a recently described variant of eccrine poroma. This neoplasm presents structural findings of hidradenoma (solid and cystic areas) and cytological characteristics of poromas (poroid and cuticular cells, the latter showing ductal differentiation). We present a case of poroid hidradenoma in a 74-year-old woman, who consulted her physician because of a nodular lesion on the left buttock

Angiohistiocitoma de células multinucleadas / Multinucleate-cell angiohistiocytoma

No disponible

No disponible

[Poroid hidradenoma]. / Hidroadenoma poroide.

Poroid hidradenoma is a recently described variant of eccrine poroma. This neoplasm presents structural findings of hidradenoma (solid and cystic areas) and cytological characteristics of poromas (poroid and cuticular cells, the latter showing ductal differentiation). We present a case of poroid hidradenoma in a 74-year-old woman, who consulted her physician because of a nodular lesion on the left buttock.