Neuropatía inducida por fármacos en un ámbito hospitalario / Drug induced neuropathy in a hospital setting

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Relación entre datos objetivos y calidad de vida percibida por el paciente con EPOC / Relationship between objective data and health-related quality of life in COPD patients

Introducción: En las enfermedades crónicas cobra especial importancia la valoración de las repercusiones de la enfermedad en el día a día de los pacientes, es decir, el estudio de su calidad de vida. La enfermedad pulmonar obstructiva crónica (EPOC) es una de las enfermedades crónicas más relevantes en nuestro país, tanto por su prevalencia como por los recursos económicos que consume. Para la valoración de la calidad de vida en estos pacientes existen cuestionarios específicos como el SGRQ, que pueden ayudarnos a conocer mejor la enfermedad y su influencia sobre la vida del paciente. En nuestro trabajo se estudia la relación del cuestionario SGRQ con la edad, el consumo de tabaco, la gravedad de la obstrucción y sus valores gasométricos. Métodos: Se seleccionaron 51 pacientes con EPOC sin comorbilidades significativas y se les administró el cuestionario SGRQ mediante entrevista personal; de cada uno de los pacientes se recogieron además los datos espirométricos, gasométricos y su historia de consumo de tabaco. Resultados: Las puntuaciones medias en cada una de las escalas del test fueron: en la escala global 40.49±18.98, en la de síntomas 34,76 ± 16,31, en la de actividad 56,68 ± 23,72 y en la de impacto 32,86 ± 19,96. Se encontraron correlaciones significativas, aunque débiles, con la edad y el FEV1, pero no con los datos gasométricos ni el consumo acumulado de tabaco. Conclusiones: Podemos concluir que, en nuestro trabajo, los parámetros que mejor se correlacionan con la calidad de vida de los pacientes con EPOC son la edad y la gravedad de la obstrucción

Introduction: In chronic diseases take special importance their influence in patient’s daily life, in other words, on its quality of life. The Chronic Obstructive Pulmonary Disease (COPD) is one of the most important chronic diseases in our country, as much by its prevalence as by its economic impact. For the assessment of the life quality in these patients, we have specific questionnaires like the SGRQ, which can help us to better know the disease and its influence on patient’s life. In our work the relationship of SGRQ with age, tobacco consumption, gasometrical data and severity of the disease are studied. Methods: 51 patients with COPD and without significant comorbidities were selected and the SGRQ was administered to them by a trained interviewer; for every patient we also recovered the gasometrical values, the spirometric data, and their tobacco consumption background. Results: The average score in each one of SGRQ scales were: global scale 40.49 ± 18.98, symptoms scale 34.76 ± 16.31, activity scale 56.68 ± 23.72 and in the impact scale 32.86 ± 19.96. We have found weak but significant correlations between the SGRQ results and the patient´s age and the FEV1, but not with the gasometrical data or with the accumulated tobacco consumption. Conclusion: We can conclude that, in our work, the parameters that better correlates objective data with health-related quality of life of COPD patients are the age and the severity of the obstruction

[Lipoid pneumonia related to an accidental aspiration of gas-oil]. / Neumonía lipoidea en relación con una aspiración accidental de gasóleo.

A 35-year-old non smoker man with no known history of chronic pulmonary disease, was treated at our hospital after accidental aspiration of gas-oil. He had developed an acute lipoid pneumonia in a few hours. Computed tomography of the chest showed a ground-glass pattern in middle lobe; given the immediate epidemiological precedent, it was possible to confirm a definitive diagnosis. One year later the patient is asymptomatic although small signs of acute process remain in the computed tomography.

Neumonía lipoidea en relación con una aspiración accidental de gasóleo / Lipoid pneumonia related to an accidental aspiration of gas-oil

Se presenta el caso de un varón de 35 años, sin historia previa de patología pulmonar crónica y no fumador, que acude al servicio de urgencias tras la aspiración accidental de gasóleo y desarrolla en el curso de unas horas una neumonía lipoidea. En la tomografía computadorizada (TC) se observa una zona en vidrio deslustrado en lóbulo medio que, junto a la presencia del antecedente epidemiológico inmediato, permite establecer el diagnóstico. Tras un año de seguimiento el paciente permanece estable y asintomático, aunque persisten en la TC leves secuelas del proceso agudo

A 35-year-old non smoker man with no known history of chronic pulmonary disease, was treated at our hospital after accidental aspiration of gas-oil. He had developed an acute lipoid pneumonia in a few hours. Computed tomography of the chest showed a ground-glass pattern in middle lobe; given the immediate epidemiological precedent, it was possible to confirm a definitive diagnosis. One year later the patient is asymptomatic although small signs of acute process remain in the computed tomography

[Relationship between objective data and health-related quality of life in COPD patients]. / Relación entre datos objetivos y calidad de vida percibida por el paciente con EPOC.

INTRODUCTION: In chronic diseases take special importance their influence in patient s daily life, in other words, on its quality of life. The Chronic Obstructive Pulmonary Disease (COPD) is one of the most important chronic diseases in our country, as much by its prevalence as by its economic impact. For the assessment of the life quality in these patients, we have specific questionnaires like the SGRQ, which can help us to better know the disease and its influence on patient s life. In our work the relationship of SGRQ with age, tobacco consumption, gasometrical data and severity of the disease are studied. METHODS: 51 patients with COPD and without significant comorbidities were selected and the SGRQ was administered to them by a trained interviewer; for every patient we also recovered the gasometrical values, the spirometric data, and their tobacco consumption background. RESULTS: The average score in each one of SGRQ scales were: global scale 40.49 +/- 18.98, symptoms scale 34.76 +/- 16.31, activity scale 56.68 +/- 23.72 and in the impact scale 32.86 +/- 19.96.We have found weak but significant correlations between the SGRQ results and the patient s age and the FEV1, but not with the gasometrical data or with the accumulated tobacco consumption. CONCLUSION: We can conclude that, in our work, the parameters that better correlates objective data with health-related quality of life of COPD patients are the age and the severity of the obstruction.

Litiasis renal en el área III de Zaragoza: bioquímica y epidemiología / Urolithiasis in the area III of Zaragoza: biochemistry and epidemiology

La urolitiasis es una enfermedad muy prevalente que ocasiona, además del sufrimiento para los pacientes, un importante coste socio sanitario. La composición de los cálculos renales, que puede influir en el tratamiento y seguimiento de la enfermedad, varía en las distintas zonas. En nuestro trabajo se estudia la composición de los cálculos recibidos en el Servicio de Bioquímica del H.C.U de Zaragoza durante el año 2002, con una breve aproximación a la epidemiología de la enfermedad en el Área III de Salud Zaragoza. La tasa de incidencia fue del 0,35% con un claro predominio en varones; Los cálculos más frecuentes fueron los de oxalato cálcico puro o combinado con carbonato de apatita, aunque el porcentaje de muestras recogidas con respecto al total de diagnósticos apenas superó el 10 %. No se encontraron diferencias significativas entre la composición de los cálculos procedentes de las distintas zonas de nuestra Área, ni en función del sexo de los pacientes. Dada la influencia de la composición del cálculo para su tratamiento, debemos insistir en la recogida del mayor número de muestras para su análisis, aunque los datos epidemiológicos y el estudio del sedimento de orina pueden ser muy útiles en la práctica diaria

The urolithiasis is a very common disease that it causes, in addition to the suffering for the patients, an important cost sanitary partner. The composition of the renal stones that can influence in the treatment and later evaluation of the disease, varies in the different zones. In our work the composition of the renal stones received in the Biochemistry department of the H.C.U of Zaragoza studies during year 2002, with a brief approach to the epidemiology of the disease in the Area III of Zaragoza. The rate of incidence was of 0.35 % with a clear predominance in men; the most frequent renal stones were those of pure calcium oxalate or calcium oxalate combined with apatite carbonate, although the percentage of samples gathered with respect to the total of diagnoses as soon as it surpassed 10%. Not found significant differences between the composition of the renal stones coming from the different zones from our Area, nor based on the sex of the patients. Given the influence of the composition of the urolithiasis for its treatment, we must insist on the collection of the greater number of samples for its analysis, although the epidemiologic data and the study of the urinary sediment can be used in the practice

[Urolithiasis in the area III of Zaragoza: biochemistry and epidemiology]. / Litiasis renal en el área III de Zaragoza: bioquímica y epidemiología.

The urolithiasis is a very common disease that it causes, in addition to the suffering for the patients, an important cost sanitary partner. The composition of the renal stones that can influence in the treatment and later evaluation of the disease, varies in the different zones. In our work the composition of the renal stones received in the Biochemistry department of the H.C.U of Zaragoza studies during year 2002, with a brief approach to the epidemiology of the disease in the Area III of Zaragoza. The rate of incidence was of 0.35% with a clear predominance in men; the most frequent renal stones were those of pure calcium oxalate or calcium oxalate combined with apatite carbonate, although the percentage of samples gathered with respect to the total of diagnoses as soon as it surpassed 10%. Not found significant differences between the composition of the renal stones coming from the different zones from our Area, nor based on the sex of the patients. Given the influence of the composition of the urolithiasis for its treatment, we must insist on the collection of the greater number of samples for its analysis, although the epidemiologic data and the study of the urinary sediment can be used in the practice.