[The recurrent ulcer patient following selective proximal vagotomy in the treatment of duodenal ulcer (author's transl)]. / Der Rezidivulcuspatient nach selektiv-proximaler Vagotomie beim Zwölffingerdarmgeschwür.

Selective proximal vagotomy (SPV) in the treatment of duodenal ulcer shows a lethality of 0% in this series. The recurrence rate is 12.4% when 60% of the patients are examined by endoscopy at a mean postoperative interval of 27 months. If only the patients with complaints had been examined by gastroscopy then ulcer recurrence would have been diagnosed in 7.1%. One-third of the recurrences are in the stomach. There is no significant difference in the recurrence rate in male or female patients, whether the ulcer is uncomplicated or complicated or SPV is done with or without pyloroplasty. Ulcers heal under further surveillance in one-third of recurrent ulcer patients; one-half of the rest have to be reoperated upon.

[Stomach movement following selective gastric vagotomy: correlation of roentgen contrast studies and electromyography in the conscious dog]. / Dei Magenmotorik nach selektiv gastraler Vagotomie: Korrelation von Röntgenkontrastuntersuchung und Elektromyographie am wachen Hund.

Electrical gastric activity in the alert dog was continuously registered by bipolar steel electrodes simultaneously with contrast x-ray studies. Delayed gastric emptying in the postoperative period following selective gastric vagotomy and pyloroplasty can be attributed to specific changes of electrical activity: 1. Electrical potential units become irregular in amplitude and frequency; 2. electrical activity of antrum is no longer synchronized with the corpus; 3. appearance of high frequency, atypical electrical activity in the antrum is associated with gastric motor inactivity; 4. peristalsis and emptying are linked to the de novo appearance of action-potential bursts.

[Electromyographic studies of the stomach following selective proximal vagotomy in the awake dog]. / Elektromyographische Untersuchungen des Magens nach selektiv proximaler Vagotomie am wachen Hund.

Electrical and mechanical activity of the stomach following selective proximal vagotomy (SPV) were studied with 79 single experiments in 10 awake dogs. The influence of several pharmacological agents and feeding was tested: 1. The AP-Index of the gastric electrical activity rises to 1. 2. High frequency, atypical electrical activity resulting in mechanical inactivity increases with the postop. time interval. It reaches 60% of measured time on the 7th postop. day. 3. Normal electrical coupling of corpus and antrum is lost. 4. Pentagastrin increases the frequency of AP-rhythm only in the denervated corpus. 5. Carbachol and insulin have no such effect. 6. Feeding decreases electrical frequency in the innervated antrum. The altered electrical activity explains the known impairment of gastric emptying following SPV. The electrical desynchronization of corpus and antrum and the increased incidence of high frequency potentials in the antrum seems to overcome the high AP-Index.