[Midfacial necrosis secondary to cocaine-abuse]. / Necrosis mediofacial secundaria al abuso de cocaína.

Midfacial necrosis due to the abuse of inhaled cocaine is a new entity that is included in the differential diagnosis of the midline destructive diseases such as Wegener's granulomatosis, polymorphic reticulosis, nasal lymphoma, infections and the idiopathic midline destructive disease. We report the case of a forty-year-old male who presented necrosis of the nasosinusal tract and optic neuropathy as complications due to the abuse of inhaled cocaine for more than twenty years and a discussion about the differential diagnosis.

Necrosis mediofacial secundaria al abuso de cocaína / Midfacial necrosis secondary to cocaine-abuse

La necrosis mediofacial secundaria al abuso continuado de cocaína intranasal es una entidad de reciente descripción que se incluye dentro del diagnóstico de las lesiones que cursan con destrucción centrofacial como son la granulomatosis de Wegener, la reticulosis polimorfa o linfoma nasal, enfermedades infecciosas y el síndrome idiopático destructivo mediofacial. Aportamos el caso de un paciente varón de 40 años que presenta necrosis del tracto nasosinusal y una neuropatía óptica unilateral como complicaciones del abuso continuado de cocaína vía nasal durante más de 20 años así como una discusión acerca del diagnóstico diferencial. (AU)

Midfacial necrosis due to the abuse of inhaled cocaine is a new entity that is included in the differential diagnosis of the midline destructive diseases such as Wegener's granulomatosis, polymorphic reticulosis, nasal lymphoma, infections and the idiopathic midline destructive disease. We report the case of a forty-year-old male who presented necrosis of the nasosinusal tract and optic neuropathy as complications due to the abuse of inhaled cocaine for more than twenty years and a discussion about the differential diagnosis (AU)

Sinusitis fúngica alérgica / Allergic fungal sinusitis

La sinusitis fúngica alérgica es una entidad clínica descrita reiteradamente que ha adquirido importancia creciente como causa de sinusitis crónica. Consiste en una enfermedad sinusal benigna, no invasiva, que está en relación con una reacción de hipersensibilidada antígenos fúngicos. Se debe sospechar en todo paciente atópico con poliposis nasal refractaria. Los hallazgos de tomografía axial computerizada (TAC) son característicos pero no diagnósticos. Para el diagnóstico es necesario demostrar la presencia de mucina alérgica en el estudio histopatológico y hifas con tinciones especiales para hongos. El tratamiento adecuado incluye la extracción de la mucina y aireación de los senos mediante cirugía endoscópica, el empleo de corticoides sistémicos postoperatorios y la inmunoterapia con antígenos fúngicos. Presentamos un caso de este tipo de sinusitis crónica describiendo los hallazgos radiológicos e histopatológicos característicos así como las teorías patogénicas y los últimos avances en inmunoterapia (AU)

Allergic fungal sinusitis is a recently described clinical entity that has gained increased attention as a cause of chronic sinusitis. Consist in a benign noninvasive sinus disease related to a hypersensitivity reaction to fungal antigens. It should be suspected in any atopic patient with refractory nasal polyps. Computed tomography (CT) findings are characteristics, but not diagnostic. Diagnosis requires show allergic mucin in the histopathologic examination and hiphae in special fungal stains. The suitable treatment includes the allergic mucin removal and sinus aeration accomplished endoscopically, perioperative systemic steroids and immunotherapy with fungal antigens. We present a case of this kind of chronic sinusitis describing the characteristic histopathologic and radiologic findings, the pathogenic theories and recent advances in immunotherapy (AU)

[Presentation of multiple oncocytic type laryngeal cysts. Clinical and histopathological findings]. / Presentación múltiple de quistes laríngeos de tipo oncocítico. Hallazgos clínicos e histopatológicos.

Oncocytic cysts are a histologically well-defined subgroup of cystic lesions of the larynx. Oncocytic cysts of the larynx are rare, clinically similar to simple laryngeal cysts, and occur as a casual finding of pathology studies. Multiple oncocytic cysts have rarely been described. Microscopic examination of laryngeal biopsies showed cysts within the lamina propria lined by oncocytic epithelium. The differential diagnosis and pathogenesis of oncocytic cysts is discussed and other laryngeal cystic lesions are reviewed.

[Rhabdomyoma in the adult]. / Rabdomioma del adulto.

Rhabdomyoma in adults is a rare benign tumor of the skeletal muscle that usually arises in the head and neck region. We report a new case of this rare tumor located in the tongue. The treatment, evolution, and anatomo-pathologic findings are described.

Rabdomioma del adulto / Rhabdomyoma of the adult

El rabdomioma del adulto es un tumor benigno derivado de la musculatura estriada, extraordinariamente infrecuente, que normalmente se localiza en la región de la cabeza y cuello. Aportamos un nuevo caso de este raro tumor, localizado en base de lengua, describiendo sus características anatomopatológicas, así como su tratamiento y evolución (AU)

Rhabdomyoma in adults is a rare benign tumor of the skeletal muscle that usually arises in the head and neck region. We report a new case of this rare tumor located in the tongue. The treatment, evolution, and anatomo-pathologic findings are described (AU)

Presentación múltiple de quistes laríngeos de tipo oncocítico. Hallazgos clínicos e histopatológicos / Presentation of multiple oncocytic type laryngeal cysts. Clinical and histopathological findings

Los quistes oncocíticos son un subgrupo patológico bien definido de lesiones quísticas de la laringe. Clínicamente similares al quiste laríngeo simple, los quistes oncocíticos laríngeos son un raro hallazgo histopatológico. La presentación múltiple de quistes oncocíticos ha sido raramente descrita. El examen microscópico de las biopsias laríngeas demuestra quistes en relación con la lámina propia, revestidos por un epitelio oncocítico. Discutimos el diagnóstico diferencial y la patogénesis de los quistes oncocíticos y revisamos otras lesiones quísticas laríngeas (AU)

Oncocytic cysts are a histologically well-defined subgroup of cystic lesions of the larynx. Oncocytic cysts of the larynx are rare, clinically similar to simple laryngeal cysts, and occur as a casual finding of pathology studies. Multiple oncocytic cysts have rarely been described. Microscopic examination of laryngeal biopsies showed cysts within the lamina propria lined by oncocytic epithelium. The differential diagnosis and pathogenesis of oncocytic cysts is discussed and other laryngeal cystic lesions are reviewed (AU)

[Allergic fungal sinusitis]. / Sinusitis fúngica alérgica.

Allergic fungal sinusitis is a recently described clinical entity that has gained increased attention as a cause of chronic sinusitis. Consist in a benign noninvasive sinus disease related to a hypersensitivity reaction to fungal antigens. It should be suspected in any atopic patient with refractory nasal polyps. Computed tomography (CT) findings are characteristics, but not diagnostic. Diagnosis requires show allergic mucin in the histopathologic examination and hiphae in special fungal stains. The suitable treatment includes the allergic mucin removal and sinus aeration accomplished endoscopically, perioperative systemic steroids and immunotherapy with fungal antigens. We present a case of this kind of chronic sinusitis describing the characteristic histopathologic and radiologic findings, the pathogenic theories and recent advances in immunotherapy.