RESUMO
The development of new therapies for inflammatory bowel disease is plagued by high costs, potential side effects, and variable levels of effectiveness. Fecal microbial transplant in inflammatory bowel diseases can offer an alternative to traditionally developed pharmacologic therapies and has demonstrated the ability to induce disease remission in randomized control trials. However, questions remain about the ultimate role of this therapy in disease management, including long term safety, and the optimal composition of transplanted stool.
Assuntos
Transplante de Microbiota Fecal/métodos , Doenças Inflamatórias Intestinais/terapia , Indução de Remissão/métodos , Transplante de Microbiota Fecal/efeitos adversos , Humanos , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do TratamentoRESUMO
The onset and progression of the auditory and vestibular difficulties which occur with typical Cogan's syndrome are outlined in this case study. These results are documented through a series of auditory and vestibular evaluations highlighting the improvement in hearing sensitivity and changes in vestibular function. The case presented is notable for the rather dramatic and sudden shifts in hearing sensitivity necessitating the use and the discontinuation of amplification.