Tomato pomace-derived nitrated fatty acids: Synthesis and antiplatelet activity.

This study investigates the antiplatelet properties of tomato pulp to combat cardiovascular diseases. Notably, it examines the formation of nitrated fatty acids (NO2-FA) in tomato pomace, renowned for its potential antiplatelet effects. Through diverse assays, including tandem mass spectrometry, microplate-based platelet aggregation, and flow cytometry, the research identifies NO2-OA, NO2-LA, and NO2-LnA as pivotal antiplatelet compounds. It demonstrates the concentration-dependent antiplatelet effects of nitrated tomato pomace against thrombin receptor activator peptide 6 (TRAP-6) and collagen-induced platelet activation, alongside the modulation of platelet activation markers. Additionally, synergistic effects were observed with nitrated tomato pomace extracts. The findings suggest therapeutic potential for NO2-FA derived from tomato pomace in preventing blood clot formation, with nitrated extracts exhibiting superior efficacy compared to non-nitrated ones. This research highlights the promising role of natural products, such as tomato pomace, in mitigating cardiovascular risks and proposes novel strategies for population health enhancement and cardiovascular disease management.

Exploring consistency between stated and revealed preferences for the plastic bag ban policy in Chile.

This paper exploits individual-level data before the implementation of a national policy to understand the factors driving avoidance of plastic consumption and explore potential inconsistencies between revealed and stated preferences for a plastic bag ban policy. We estimate a bivariate ordered probit model that allows us to account for a potential correlation between these types of preferences. The data reveals that while 71% of respondents take a reusable bag for shopping, only 58% of the sample state to strongly agree with prohibiting plastic bags. We find that gender, age, environmental concerns, environmental efforts, participation in environmental causes and pro-environmental behavior determine avoidance of plastic consumption, but no effects are found for being in favor of the prohibition. We also find inconsistencies decrease for individuals demonstrating higher pro-environmental behavior in related domains. This indicates waste management policies may benefit from local grounded knowledge from related environmental initiatives.