Factores de riesgo de hipertensión arterial en nativos de Isla de Pascua / Risk factors for hypertension in natives from Easter Island

Blood pressure, weight and cardiovascular risk factors were evaluated in 73 adults of Easter island (mean age 49 ñ 12.9 (SD) years) in January 1989 and 1990. Their mean blood pressure (BP) was 129 ñ 24/81 ñ 14, significantly higher by 7/5 mmHg than in 1979 (p < 0.05). Of the population studied 30% of subjects were hypertensives. Both systolic 9S) and diastolic blood pressure (DBP) correlated with age (r=0.40, p < 0.005 and r = 24,p < 0.05 respectively). In males body mass index correlated strongly with SBP and DBP (r = 0.55, p < 0.005 and r = 0.52,p < 0.01). Forty eight % of subjects were obese, 60% smoked (14 cigarettes/day), 38% drank alcohol and 70% lead sedentary lifes; their level of stress was considered average. In 23 normotensives or undiagnosed hypertensives 24 hour urine was collected for sodium, potassium, creatinine and kallikrein; mean urinary sodium exretion was 121 ñ 30 mmol/day; potassium excretion 59 ñ 29 mmol/day, creatinine excretion 1383 mg/day and kallikrein excretion 682 ñ 355 m/day; of these, only urinary sodium was significantly lower than values determined in a group of 29 continental volunteers. Eleven natives that had never left the island had similatr BP and risk factors than a sex and age paired sample, who has spent 10.9 ñ 7.8 years in the continent. The present study demostrates that Easter Island natives have increased their mean BP in 10 years, elevated their BP with age and have lost the protection previously associated to staying in the island. In this sample the prevalence of hypertension (30%) was high. We postulate that the 2 main factors determining the BP elevation are a sodiumintake greater than 100 mmol/day and a high prevalence of obesity, which plays a stronger hypertensogenic role in males. It is highly probable that the contamination is due to returning migrants and to the massive entry of tourists

Aplicación de un índice de estabilidad fisiológica en unidad de cuidados intensivos pediátrica / Use of a psysiologic stability index in a pediatric intensive care unit

Se aplicó el Indice de Estabilidad Fisiológica (PSI) a todos los pacientes ingresados a la UCI pediátrica del Hospital Clínico de la Universidad Católica de Chile en el período comprendido entre abril de 1987 y agosto de 1988. La edad de los pacientes varió entre los 10 días de vida y los 15 años de edad y se evaluaron 152 niños. El PSI fue aplicado durante los 4 primeros días de estadía de dichos pacientes en la UCI y se obtuvo una calificación promedio que se correlacionó con la probabilidad de morir mediante un análisis de regresión logística. Mediante un análisis de varianza se logró determinar que existen diferencias significativas entre la calificación de los no-sobrevivientes (21,71 puntos) y la calificación máxima de los sobrevivientes (9,39 puntos), según la prueba T de Student