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1.
Sci Rep ; 12(1): 6276, 2022 04 15.
Artigo em Inglês | MEDLINE | ID: mdl-35428771

RESUMO

Optimisation of models applied in sheet erosion equations could facilitate effective management of sheet erosion in the field, and sustainable agricultural production. To optimise the characterisation of sheet erosion on slope farmland in South China, the present study conducted field simulation rainfall experiments with vegetated and fallow soils. According to the results, sheet erosion rate first increased with an increase in rainfall duration and then stabilised. Exclusive P. vulgaris planting and P. vulgaris in combination with earthworms could reduce sheet erosion by 10-60%, and the combined method could better control sheet erosion. There were significant differences in erosion rate between mild and steep slopes, and light and heavy rain conditions. The influence of rain intensity on sheet erosion was greater than that of slope. Soil organic matter (SOM), rain intensity, and slope can be used to optimise sheet erosion equations of exposed slopes, and SOM and hydraulic parameters can be used to optimise sheet erosion equations in vegetated slopes. The results of the present study could facilitate the reduction of the time and space variability errors in the establishment of sheet erosion models for vegetated slopes.


Assuntos
Chuva , Solo , Agricultura , China , Conservação dos Recursos Naturais , Fazendas , Movimentos da Água
2.
Immunol Invest ; 46(4): 375-384, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28375762

RESUMO

Constitutive or excessive activation of Toll-like receptor (TLR) signaling pathway can disrupt the body's immune tolerance to autoantigen, thus promoting the development of autoimmune disease. However, the expression profile of TLR signaling pathway in peripheral blood neutrophils in the pathogenesis of microscopic polyangiitis (MPA) remains unclear. Thus, improved understanding of the pathobiology of this disease may aid in the development of therapeutic targets for patients with MPA. In the present study, we assessed the expression of TLR signaling pathway-related genes in peripheral blood neutrophils in patients with MPA. PCR array analysis was performed on 20 patients with MPA and 12 healthy controls. Gene expression profile was performed using the human TLR for autoimmunity and inflammation PCR array of Genecopoeia, containing 84 genes related to TLR signaling pathway and six house-keeping genes. We then used quantitative real-time PCR to validate the array test. The array results identified 13 upregulated genes and 5 genes which were downregulated. The resulting qRT-PCR was consistent with the findings by PCR array. Our results suggest that peripheral blood neutrophils display changes in the expression of TLR signaling pathway-related genes associated with the pathogenesis of microscopic polyangiitis.


Assuntos
Poliangiite Microscópica/imunologia , Neutrófilos/imunologia , Receptores Toll-Like/metabolismo , Adulto , Idoso , Circulação Sanguínea , Feminino , Regulação da Expressão Gênica , Humanos , Masculino , Pessoa de Meia-Idade , Transdução de Sinais , Receptor 10 Toll-Like/genética , Receptor 10 Toll-Like/metabolismo , Receptor 6 Toll-Like/genética , Receptor 6 Toll-Like/metabolismo , Receptor 7 Toll-Like/genética , Receptor 7 Toll-Like/metabolismo , Receptores Toll-Like/genética , Transcriptoma , Adulto Jovem
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