RESUMO
Congenital bilateral pseudoarthrosis is an extremely rare condition. We report a neonate with bilateral congenital clavicle pseudoarthrosis. The neonate had a palpable gap bilaterally. Radiological examination confirmed the diagnosis. The baby had a complete spontaneous healing in a year. We review the recent literature.
RESUMO
Hajdu-Cheney syndrome (HCS) is a rare disorder principally characterized by acro-osteolysis, distinctive craniofacial and skull changes, dental anomalies and short stature. A common finding in HCS patients is secondary osteoporosis that progresses over time and contributes to various skeletal problems, especially fractures. Although autosomal dominant inheritance has been documented in several families, sporadic (non-familial) cases have also been reported. Here, a case of a 9-year-old girl with familial HCS and multiple spinal fractures, who has been effectively treated with pamidronate, is presented. This is the first report of a beneficial effect of intravenous bisphosphonate administration on a child with HCS-related osteoporosis.
Assuntos
Anormalidades Múltiplas , Conservadores da Densidade Óssea/administração & dosagem , Densidade Óssea/efeitos dos fármacos , Difosfonatos/administração & dosagem , Síndrome de Hajdu-Cheney/tratamento farmacológico , Osteoporose/tratamento farmacológico , Acro-Osteólise/tratamento farmacológico , Criança , Esquema de Medicação , Feminino , Seguimentos , Síndrome de Hajdu-Cheney/genética , Síndrome de Hajdu-Cheney/patologia , Humanos , Bombas de Infusão , Osteoporose/genética , Osteoporose/patologia , Fraturas por Osteoporose/etiologia , Pamidronato , Linhagem , Fraturas da Coluna Vertebral/tratamento farmacológico , Fraturas da Coluna Vertebral/genética , Fraturas da Coluna Vertebral/prevenção & controle , Fatores de Tempo , Resultado do TratamentoRESUMO
There is some evidence that the anterior tibial vascular tree is poorly developed in children with club foot. We have found a significantly greater prevalence of absence of the dorsalis pedis pulse in the parents of such children. We also found significantly more tobacco smokers among the club-foot parents than in the control group.
Assuntos
Pé Torto Equinovaro/genética , Pé Torto Equinovaro/fisiopatologia , Pé/irrigação sanguínea , Pulso Arterial/fisiologia , Adolescente , Adulto , Artérias/diagnóstico por imagem , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Pais , UltrassonografiaRESUMO
Calcaneal fractures in very young children are thought to be rare. We report on seven calcaneal fractures in children under the age of 36 months in the absence of a history of significant injury. In five cases plain radiology was normal, but the diagnosis was reached using scintigraphy. We suggest that this is not such a rare injury, and that wider use of scintigraphy will assist in making the diagnosis. The prognosis of this injury is excellent.
Assuntos
Calcâneo/lesões , Fraturas Fechadas/diagnóstico por imagem , Calcâneo/diagnóstico por imagem , Pré-Escolar , Humanos , Lactente , Radiografia , CintilografiaRESUMO
Development of osteomyelitis in a closed fracture is very rare. Although it has been reported that trivial trauma may be associated with the subsequent development of acute osteomyelitis, Waldovel et al. (1970) found no evidence that fractures were involved in the etiology of osteomyelitis. We report a case in which the infection, after a closed fracture involved both metaphyses and the diaphysis of the radius.
