RESUMO
Detection of human papilloma virus in genitals lesions by molecular hybridization. Some H.P.V. types are sexually transmitted and infect genital organs. We have used molecular hybridization to examine the distribution of H.P.V. 6 or II and H.P.V. 16 in benign, premalignant and malignant genital lesions from 344 patients. The frequency of H.P.V. 16 positive cases increases as the cervical lesions progress to malignancy: 57/78 are positive (73%) in the carcinomas, 29/83 are positive (35%) in mild or moderate dysplasia. The majority of benign condylomata acuminata harbors DNA of other types, namely H.P.V. 6 and II.
Assuntos
Carcinoma/microbiologia , Condiloma Acuminado/microbiologia , Sondas de DNA de HPV , DNA Viral/análise , Neoplasias dos Genitais Femininos/microbiologia , Papillomaviridae/isolamento & purificação , Infecções Tumorais por Vírus/microbiologia , Displasia do Colo do Útero/microbiologia , Southern Blotting , Carcinoma in Situ/microbiologia , Feminino , Humanos , Invasividade Neoplásica , Hibridização de Ácido Nucleico , Papillomaviridae/classificação , Neoplasias do Colo do Útero/microbiologiaRESUMO
The purpose of this study was to determine the prevalence of herpes simplex virus antibodies among the population in Algiers. Anti-bodies to HSV1 are acquired rapidly between the ages of 1 and 6 years and 81.25% of the population is HSV1 seropositive by 15 years of age. Patients suffering from genital disorders possess HSV type 2 antibodies at a rate significantly higher (p less than 0.001) than in the control group.
