Enantioselective Synthesis of 4- and 6-Azaindolines by a Cation-Directed Cyclization.

Functionalized 4- and 6-azaindolines are accessible with high levels of enantioselectivity by the cation-directed cyclization of aminopyridine-derived imines via phase-transfer catalysis. The extension of this methodology to diastereoselective cyclizations is also described.