RESUMO
Ovarian cancer is the fifth most common cancer in women in France with 4714 new cases in 2017. More than 70% of patients whose disease is initially locally advanced will present locoregional or distant recurrence. Therapeutic options in this situation are not consensual. They are based on chemotherapy possibly associated with an iterative cytoreductive surgery when it is bearable by the patient. The place of radiotherapy in the management of the disease is hidden in the vast majority of national or international standards. We conducted a general review of the literature to clarify the role of irradiation in the global management of ovarian cancers, particularly in recurrence.
Assuntos
Recidiva Local de Neoplasia/radioterapia , Neoplasias Ovarianas/radioterapia , Antineoplásicos/uso terapêutico , Feminino , Humanos , Recidiva Local de Neoplasia/classificação , Neoplasias Ovarianas/classificação , Cuidados Paliativos/métodos , Radiocirurgia/métodos , Radioterapia Adjuvante , Radioterapia Conformacional/métodosRESUMO
PURPOSE: To evaluate the dosimetric gain obtained in either the planning target volume or organs at risk coverage by the use of intensity-modulated radiation therapy in some particular postoperative breast cancers. PATIENTS AND METHOD: Prospective dosimetric comparison between monoisocentric conformal radiotherapy and intensity-modulated radiation therapy in nine patient files. RESULTS: Using intensity-modulated radiation therapy was shown to improve in each case, at least one conformity, homogeneity, and coverage index either for planning target volumes or for organs at risk. Intensity-modulated radiation therapy was therefore always chosen rather than conformal monoisocentric radiotherapy. CONCLUSIONS: Indications to retain intensity-modulated radiation therapy would consist of bilateral lesions, pectus excavatum, past thoracic irradiation (Hodgkin's disease) and complex volumes in obese or overweight patients.