RESUMO
The authors report a case of an intraosseous cyst located in the distal end of the tibia. A typical subchondral defect with a narrow opening in the ankle joint was well defined by CT scan and MRI. The diagnostic value of noninvasive techniques and differential diagnosis are specified after a review of the literature.
Assuntos
Articulação do Tornozelo/diagnóstico por imagem , Cisto Sinovial/diagnóstico , Tíbia/diagnóstico por imagem , Adulto , Diagnóstico Diferencial , Humanos , Imageamento por Ressonância Magnética , Masculino , Cisto Sinovial/diagnóstico por imagem , Cisto Sinovial/etiologia , Tomografia Computadorizada por Raios XRESUMO
The authors report about one case of false aneurysm in the right subclavicular pit, which developed after iterative venous punctures in a 67-year-old woman. Surgery was excluded, and an endovascular treatment was decided, with an approach of the lesion by direct puncture in this case and the insertion of an inflatable balloon.
Assuntos
Aneurisma/etiologia , Cateterismo , Veia Subclávia/diagnóstico por imagem , Idoso , Aneurisma/diagnóstico por imagem , Aneurisma/terapia , Diagnóstico Diferencial , Feminino , Humanos , Doença Iatrogênica , Punções/efeitos adversos , RadiografiaRESUMO
In rats poisoned with soman (s.c. 100 micrograms/kg), a potent inhibitor of cholinesterase (ChE), the numbers of dendritic spines of Golgi impregnated hippocampal pyramidal cells (CA1 sector) were evaluated within the first hour of the intoxication. Animals that experienced convulsions showed a rapid and striking decrease in the density of dendritic spines which could be reduced by nearly 80% of the controls in the basal dendrites 60 min post-soman exposure. Although the exact mechanisms cannot be determined from the present study, it is suggested that the spine loss may represent: (1) the first sign of the seizure-related neuronal changes which are known to occur later during soman intoxication; and (2) the expression of the 'dendrotoxic' effects produced by certain non-cholinergic excitatory transmitters such as glutamate.
Assuntos
Dendritos/efeitos dos fármacos , Hipocampo/citologia , Neurônios/fisiologia , Tratos Piramidais/citologia , Soman/toxicidade , Animais , Dendritos/fisiologia , Hipocampo/efeitos dos fármacos , Hipocampo/fisiologia , Masculino , Microscopia , Neurônios/efeitos dos fármacos , Tratos Piramidais/efeitos dos fármacos , Tratos Piramidais/fisiologia , Ratos , Ratos Endogâmicos , Convulsões/patologia , Convulsões/fisiopatologiaRESUMO
Paragangliomas of the carotid body are uncommon tumours usually regarded as benign or locally malignant. Metastasis occurs in 5 to 25% of the cases, involving mainly the liver, lung and bones. A case of carotid body tumour without histological evidence of malignancy but with local invasion and, subsequently, multiple spinal metastases is reported. Since the histological prognosis of the initial tumour is impossible to make in most cases, the authors underline the importance of signs of local invasion which is predictive of metastasis and requires regular monitoring with radionuclide bone scanning and MRI.