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1.
Clin Case Rep ; 11(5): e7283, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37151940

RESUMO

Key Clinical Message: We present the case of a rare obstetric emergency, which is usually fatal. Our case highlights suspicion of AFLP in patients presenting with jaundice in the third trimester with good maternal and fetal outcomes after a timely intervention. Abstract: Acute fatty liver of pregnancy (AFLP) is a rare, obstetric emergency characterized by maternal liver dysfunction that can lead to maternal and fetal complications. We report a case of 28-year-old primigravida 39 weeks gestation diagnosed with AFLP complicated by coagulopathy with good maternal and fetal outcomes after a timely intervention.

2.
JNMA J Nepal Med Assoc ; 61(260): 379-382, 2023 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-37208883

RESUMO

Toxic epidermal necrolysis in pregnancy is a rare disease that can have an adverse effect on Toxic epidermal necrolysis in pregnancy is a rare disease that can have an adverse effect on pregnancy outcomes. Common etiology of the condition includes medication triggered followed by mycoplasma infection. Almost one-third of cases are idiopathic. Despite the rarity of data, terbinafine causing toxic epidermal necrolysis has been reported. Toxic epidermal necrolysis manifests as a macule, erythema followed by a blister in the chest and spreading to other parts of the body. Removal of the offending agent and supportive management is the cornerstone of management. Here we report 22-year-old primipara pregnant women presenting with toxic epidermal necrolysis after 3 weeks of oral terbinafine use with good pregnancy outcomes. Keywords: case reports; pregnancy; Stevens-Johnson syndrome; toxic epidermal necrolysis.


Assuntos
Síndrome de Stevens-Johnson , Gravidez , Humanos , Feminino , Adulto Jovem , Adulto , Síndrome de Stevens-Johnson/diagnóstico , Síndrome de Stevens-Johnson/etiologia , Terbinafina/efeitos adversos , Doenças Raras/complicações
3.
Clin Case Rep ; 11(2): e6932, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36789317

RESUMO

Pheochromocytoma is often diagnosed prior to pregnancy. Sometimes, the disease may be diagnosed for the first-time during pregnancy masking itself as a hypertensive disease in pregnancy. Early diagnosis and timely, appropriate management reduce possible maternal and fetal complications. We identified a case of pheochromocytoma during pregnancy misdiagnosed as preeclampsia.

4.
Clin Case Rep ; 10(6): e6006, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35782222

RESUMO

Far migrated IUCD (Intrauterine Contraceptive Device) is an uncommon condition that has different manifestations depending upon its location. We present the case of a 22-year-old primipara who had a spontaneous abortion after IUCD placement and suffered chronic right lower abdominal pain thereafter. Diagnostic laparoscopy revealed Cu-IUCD in the right iliac fossa.

5.
JNMA J Nepal Med Assoc ; 60(251): 641-643, 2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-36705190

RESUMO

Pemphigus vulgaris is a rare autoimmune mucocutaneous blistering disease clinically presenting as vesicles, bullae, and erosion and histologically characterized by suprabasal split and acantholysis. It usually affects mucous membranes and skin. Recurrent oral ulcers can only be the clinical manifestation before progressing into skin lesions. This can lead to the delayed diagnosis of this disease. Here we report a case of pemphigus vulgaris which was diagnosed after years of suffering from an oral ulcer that eventually progressed to widespread skin blistering and ulceration. The patient was treated with oral prednisolone which showed improvement within a week. Physicians should consider the differential diagnosis of pemphigus vulgaris in patients presenting with a recurrent oral ulcer. Keywords: delayed diagnosis; oral ulcer; pemphigus vulgaris.


Assuntos
Úlceras Orais , Pênfigo , Humanos , Pênfigo/diagnóstico , Pênfigo/tratamento farmacológico , Úlceras Orais/diagnóstico , Úlceras Orais/etiologia , Úlceras Orais/tratamento farmacológico , Diagnóstico Tardio , Prednisolona/uso terapêutico , Pele/patologia
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