[Several indicators of tissue oxygen during modeling of extravehicular activity of man]. / Nekotorye pokazateli kislorodnogo rezhima tkanei pri modelirovanii vnekorabel'noi deiatel'nosti cheloveka.

Investigations of tissue oxygen indices during simulation of extravehicular activity (EVA) of cosmonauts demonstrated that breathing pure oxygen at approximately 280 mmHg elevates oxygen tension in capillary blood, and capillary-tissue gradient during physical work. Physical work alone stimulates tissue oxygenation due to, apparently, intensification of the processes of oxidative phosphorylation. The observed shifts in oxygen status reverse significantly within the first 5 min after completion of the experiment.

[Oxygen tension and water-soluble products of lipid peroxidation in blood of volunteers in hypobaric hyperoxia]. / Napriazhenie kisloroda i vodorastvorimye produkty perekisnogo okisleniia lipidov v krovi ispytuemykh pri gipobaricheskoi giperoksii.

Oxygen tension in the arterial blood with transcutaneous method (tcPO2) and TBA-active products of venous blood plasma were measured during simulation of extravehicular activity. There was a parallel increase of tcPO2 and the level of TBA-active products upon introduction of hypobaric hyperoxia factor. Detrimental action of lipid peroxidation products on erythrocyte membranes can be one of the factors of anemia during space flight.

[Changes in the hemodynamics and cardiac function of hypertension patients on moderate limited consumption of table salt]. / Izmenenie gemodinamiki i funktsional'nogo sostoianiia serdtsa pri umerennom ogranichenii potrebleniia povarennoi soli u bol'nykh gipertonicheskoi bolezn'iu.

A total of 50 patients with essential hypertension, I-II stages, were investigated to study changes in peripheral and intracardiac hemodynamics and myocardial contractility in moderate restriction of sodium chloride in "salt-sensitive" patients (SSP). In such patients (84% of all examinees) with mild arterial hypertension moderate restriction of SC consumption causes a sufficient antihypertensive effect determined by considerable improvement of peripheral hemodynamic indices and improvement of myocardial pump function and contractility, and in patients with moderate and severe hypertension it potentiates an antihypertensive effect and influence of drug therapy on hemodynamics. In non-SSP moderate restriction in SC consumption was ineffective. A sufficient antihypertensive effect in them resulted from the use of drug therapy at higher dosage than in SSP.