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1.
IEEE Trans Pattern Anal Mach Intell ; 37(4): 697-712, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26353288

RESUMO

The bag-of-systems (BoS) representation is a descriptor of motion in a video, where dynamic texture (DT) codewords represent the typical motion patterns in spatio-temporal patches extracted from the video. The efficacy of the BoS descriptor depends on the richness of the codebook, which depends on the number of codewords in the codebook. However, for even modest sized codebooks, mapping videos onto the codebook results in a heavy computational load. In this paper we propose the BoS Tree, which constructs a bottom-up hierarchy of codewords that enables efficient mapping of videos to the BoS codebook. By leveraging the tree structure to efficiently index the codewords, the BoS Tree allows for fast look-ups in the codebook and enables the practical use of larger, richer codebooks. We demonstrate the effectiveness of BoS Trees on classification of four video datasets, as well as on annotation of a video dataset and a music dataset. Finally, we show that, although the fast look-ups of BoS Tree result in different descriptors than BoS for the same video, the overall distance (and kernel) matrices are highly correlated resulting in similar classification performance.

2.
IEEE Trans Pattern Anal Mach Intell ; 36(3): 521-35, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24457508

RESUMO

The problem of cross-modal retrieval from multimedia repositories is considered. This problem addresses the design of retrieval systems that support queries across content modalities, for example, using an image to search for texts. A mathematical formulation is proposed, equating the design of cross-modal retrieval systems to that of isomorphic feature spaces for different content modalities. Two hypotheses are then investigated regarding the fundamental attributes of these spaces. The first is that low-level cross-modal correlations should be accounted for. The second is that the space should enable semantic abstraction. Three new solutions to the cross-modal retrieval problem are then derived from these hypotheses: correlation matching (CM), an unsupervised method which models cross-modal correlations, semantic matching (SM), a supervised technique that relies on semantic representation, and semantic correlation matching (SCM), which combines both. An extensive evaluation of retrieval performance is conducted to test the validity of the hypotheses. All approaches are shown successful for text retrieval in response to image queries and vice versa. It is concluded that both hypotheses hold, in a complementary form, although evidence in favor of the abstraction hypothesis is stronger than that for correlation.

3.
IEEE Trans Pattern Anal Mach Intell ; 35(7): 1606-21, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23681990

RESUMO

Dynamic texture (DT) is a probabilistic generative model, defined over space and time, that represents a video as the output of a linear dynamical system (LDS). The DT model has been applied to a wide variety of computer vision problems, such as motion segmentation, motion classification, and video registration. In this paper, we derive a new algorithm for clustering DT models that is based on the hierarchical EM algorithm. The proposed clustering algorithm is capable of both clustering DTs and learning novel DT cluster centers that are representative of the cluster members in a manner that is consistent with the underlying generative probabilistic model of the DT. We also derive an efficient recursive algorithm for sensitivity analysis of the discrete-time Kalman smoothing filter, which is used as the basis for computing expectations in the E-step of the HEM algorithm. Finally, we demonstrate the efficacy of the clustering algorithm on several applications in motion analysis, including hierarchical motion clustering, semantic motion annotation, and learning bag-of-systems (BoS) codebooks for dynamic texture recognition.

4.
Neural Comput ; 24(6): 1391-407, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22364501

RESUMO

The concave-convex procedure (CCCP) is an iterative algorithm that solves d.c. (difference of convex functions) programs as a sequence of convex programs. In machine learning, CCCP is extensively used in many learning algorithms, including sparse support vector machines (SVMs), transductive SVMs, and sparse principal component analysis. Though CCCP is widely used in many applications, its convergence behavior has not gotten a lot of specific attention. Yuille and Rangarajan analyzed its convergence in their original paper; however, we believe the analysis is not complete. The convergence of CCCP can be derived from the convergence of the d.c. algorithm (DCA), proposed in the global optimization literature to solve general d.c. programs, whose proof relies on d.c. duality. In this note, we follow a different reasoning and show how Zangwill's global convergence theory of iterative algorithms provides a natural framework to prove the convergence of CCCP. This underlines Zangwill's theory as a powerful and general framework to deal with the convergence issues of iterative algorithms, after also being used to prove the convergence of algorithms like expectation-maximization and generalized alternating minimization. In this note, we provide a rigorous analysis of the convergence of CCCP by addressing two questions: When does CCCP find a local minimum or a stationary point of the d.c. program under consideration? and when does the sequence generated by CCCP converge? We also present an open problem on the issue of local convergence of CCCP.

5.
Genome Res ; 15(5): 724-36, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15867433

RESUMO

A large gene expression database has been produced that characterizes the gene expression and physiological effects of hundreds of approved and withdrawn drugs, toxicants, and biochemical standards in various organs of live rats. In order to derive useful biological knowledge from this large database, a variety of supervised classification algorithms were compared using a 597-microarray subset of the data. Our studies show that several types of linear classifiers based on Support Vector Machines (SVMs) and Logistic Regression can be used to derive readily interpretable drug signatures with high classification performance. Both methods can be tuned to produce classifiers of drug treatments in the form of short, weighted gene lists which upon analysis reveal that some of the signature genes have a positive contribution (act as "rewards" for the class-of-interest) while others have a negative contribution (act as "penalties") to the classification decision. The combination of reward and penalty genes enhances performance by keeping the number of false positive treatments low. The results of these algorithms are combined with feature selection techniques that further reduce the length of the drug signatures, an important step towards the development of useful diagnostic biomarkers and low-cost assays. Multiple signatures with no genes in common can be generated for the same classification end-point. Comparison of these gene lists identifies biological processes characteristic of a given class.


Assuntos
Algoritmos , Classificação/métodos , Regulação da Expressão Gênica , Análise de Sequência com Séries de Oligonucleotídeos/métodos , Análise de Sequência com Séries de Oligonucleotídeos/normas , Preparações Farmacêuticas/metabolismo , RNA Mensageiro/isolamento & purificação , Animais , Medula Óssea/metabolismo , Relação Dose-Resposta a Droga , Rim/metabolismo , Fígado/metabolismo , Modelos Logísticos , Masculino , Miocárdio/metabolismo , Análise de Componente Principal , Ratos , Ratos Sprague-Dawley , Reprodutibilidade dos Testes
6.
Bioinformatics ; 20(16): 2626-35, 2004 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-15130933

RESUMO

MOTIVATION: During the past decade, the new focus on genomics has highlighted a particular challenge: to integrate the different views of the genome that are provided by various types of experimental data. RESULTS: This paper describes a computational framework for integrating and drawing inferences from a collection of genome-wide measurements. Each dataset is represented via a kernel function, which defines generalized similarity relationships between pairs of entities, such as genes or proteins. The kernel representation is both flexible and efficient, and can be applied to many different types of data. Furthermore, kernel functions derived from different types of data can be combined in a straightforward fashion. Recent advances in the theory of kernel methods have provided efficient algorithms to perform such combinations in a way that minimizes a statistical loss function. These methods exploit semidefinite programming techniques to reduce the problem of finding optimizing kernel combinations to a convex optimization problem. Computational experiments performed using yeast genome-wide datasets, including amino acid sequences, hydropathy profiles, gene expression data and known protein-protein interactions, demonstrate the utility of this approach. A statistical learning algorithm trained from all of these data to recognize particular classes of proteins--membrane proteins and ribosomal proteins--performs significantly better than the same algorithm trained on any single type of data. AVAILABILITY: Supplementary data at http://noble.gs.washington.edu/proj/sdp-svm


Assuntos
Algoritmos , Mapeamento Cromossômico/métodos , Bases de Dados de Proteínas , Perfilação da Expressão Gênica/métodos , Modelos Genéticos , Proteínas/genética , Análise de Sequência de Proteína/métodos , Inteligência Artificial , Bases de Dados Genéticas , Proteínas Fúngicas/química , Proteínas Fúngicas/genética , Genômica/métodos , Armazenamento e Recuperação da Informação/métodos , Proteínas de Membrana/genética , Proteínas de Membrana/metabolismo , Modelos Estatísticos , Reconhecimento Automatizado de Padrão , Proteínas/análise , Proteínas/química , Proteínas/classificação , Proteínas Ribossômicas/química , Proteínas Ribossômicas/genética , Alinhamento de Sequência , Homologia de Sequência de Aminoácidos , Integração de Sistemas
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