[Experience with physiotherapy in a posttraumatic neurodystrophic syndrome of the extremities]. / Opyt fizioterapii pri posttravmaticheskom neirodistroficheskom sindrome konechnostei.

Combined pathogenetic treatment including physiotherapy, drugs, massage, exercise was tested in 98 patients with posttraumatic neurodystrophic syndrome in phase II and III. The responses achieved made it possible to recommend the above regimen for wide application in rehabilitation centers and clinics.

[Several indicators of oxidative processes in fractures of the long bones]. / O nekotorykh pokazateliakh okislitel'nykh protsessov pri perelomakh dlinnykh kostei.

The authors have observed 55 patients with fresh fractures, with disturbances in consolidation (delayed consolidation, non-union of fractures, false joints) and with defects of diaphyses of the long bones. In the fracture area the dynamics of oxidation-reduction potential (ORP) was studied and volarographic investigations (determination of the volumetric speed of the local blood flow by hydrogen, a test with oxygen load) were carried out. Certain correlation between the quantity and the dynamics of the values under study and the state of the consolidation process was established. Coincidence of the dynamics of ORP and the local blood flow, presence of the quantity of volumetric speed of the local blood flow of 25-30 ml/min per 100 g of tissue with rather high ORP and a positive test under oxygen load in the polarographic study were prognostically favourable. The applied methods allow to control the course of the process of consolidation of the fragments and to a certain extent prognosticate the results of treatment of the patients with fractures of the long bones.

[Electron microscopic study of reparative osteogenesis following electric stimulation of bony tissue regeneration]. / Elektronno-mikroskopicheskoe issledovannie reparativnogo osteogeneza v usloviiakh élektrostimuliatsii regeneratisii kostnoi tkani.

Electron microscopy was used to study the regenerating bone tissue in experimental resection of the diaphysis fragment of the rabbit radius under osteogenesis stimulation by means of pulsed low-frequency electric current. Proliferation and differentiation of fibroblasts and osteoblasts of the bone regenerating tissue were more active under electric stimulation. Hypertrophy and hyperplasia of cell organelles occurred earlier as compared with control. Cell secretion was found to be intensified, manifesting by output of greater amounts of collagen protein. As a result of changes listed, the newly formed bone tissue rapidly filled the defect between the fragments.

[Mechanism of the stimulating effect of an electric current on reparative regeneration of bone tissue]. / K voprosu o mekhanizme stimuliruiushchego deistviia élektricheskogo toka na reparativnuiu regneratsiiu kostnoi tkani.

Experiments were conducted on rabbits. Changes in ATP in the regenerating bone tissue after incomplete osteotomy and removal of a bone section, and also in cases of reparative osteogenesis stimulation in the region of the bone defect by means of pulse electric current were studied. ATP content in the bone callus after incomplete osteotomy and electrostimulation proved to exceed such in the regenerating bone tissue following removal of the bone fragment when no stimulation was applied. On the basis of the data obtained it is suggested that improvement of energy provision of the fracture consolidation process was one of the important links in the mechanism of stimulating influence of the electric current on the reparative regeneration of the bone tissue.