1.
Cardiovascular effects of particulate air pollution exposure: time course and underlying mechanisms.
J Intern Med
; 272(3): 224-39, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22724512
RESUMO
Air pollution is now recognized as an important independent risk factor for cardiovascular morbidity and mortality and may be responsible for up to 3 million premature deaths each year worldwide. The mechanisms underlying the observed effects are poorly understood but are likely to be multifactorial. Here, we review the acute and chronic effects of air pollution exposure on the cardiovascular system and discuss how these effects may explain the observed increases in cardiovascular morbidity and mortality.
Assuntos
Poluição do Ar/efeitos adversos , Doenças Cardiovasculares/etiologia , Exposição Ambiental/efeitos adversos , Material Particulado , Velocidade do Fluxo Sanguíneo/fisiologia , Pressão Sanguínea/fisiologia , Endotélio Vascular/fisiopatologia , Fibrinólise/fisiologia , Frequência Cardíaca/fisiologia , Humanos , Inflamação/etiologia , Estresse Oxidativo/fisiologia , Rigidez Vascular/fisiologia , Vasoconstrição/fisiologia
2.
Intern Med J
; 38(12): 875-8, 2008 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19120545
3.
Nature
; 225(5237): 1005-6, 1970 Mar 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16056897
RESUMO
Is the most profit to be had from research inspired by curiosity or by foresight of practical applications? A recent suggestion that the answer could be found by evaluating curiosity-oriented projects has proved hard to follow up.