Gigantomastia in a patient with systemic lupus erythematosus successfully treated by reduction mammoplasty.

The objective of the study was to describe a Filipino woman with systemic lupus erythematosus (SLE) who developed gigantomastia associated with hyperoestrogenemia and successfully treated by reduction mammoplasty. A 37-year-old Filipino woman with SLE of 5-year duration presented with enlargement of breasts, which became more noticeable and progressive during disease flares requiring increased steroid dose (+ or - 40 mg/day). Following control of the last SLE flare, with prednisone effectively tapered to 15 mg/day, she consented to surgical breast reduction. Preoperative physical examination recorded the right and left breast measurement of 61 cm and 54.5 cm from sternal notch to nipple tip, respectively. serum oestrogen assay was elevated. She successfully underwent reduction mammoplasty with free nipple graft, with an uneventful postoperative course. The breast tissue oestrogen and progesterone receptor assays were strongly positive. In the succeeding months, SLE disease remained stable with prednisone tapered to 10 mg daily. This case illustrates a rare occurrence of gigantomastia associated with hyperoestrogenemia in a patient with SLE, successfully treated with reduction mammoplasty.

Buschke-Lowenstein tumor and pregnancy: a case report.

Buschke-Lowenstein tumor is a giant condyloma acuminatum that arises on the male and female anogenital region. It is considered a histologically benign tumor but carries a risk of malignant transformation. Early diagnosis and treatment are advised and the choice of treatment is crucial. We present a case of a 31-year-old pregnant woman with myasthenia gravis affected by Buschke-Lowenstein tumor.

Fallopian tube carcinoma: incidental finding during surgery for acute pelvic inflammatory disease--case report.

BACKGROUND: Primary carcinoma of the fallopian tube is a rare condition. Preoperative diagnosis is difficult and in most cases it is an intraoperative finding or a histopathological diagnosis. CASE: A 49-year-old woman presented with pelvic pain, fever (38 degrees C), elevated white blood cell count and a right adnexal mass. Pelvic inflammatory disease was suspected and broad spectrum antibiotics were established. Five days later, due to lack of clinical response, a total abdominal hysterectomy, bilateral salpingo-oophorectomy and appendectomy were performed. Histopathology showed a primary fallopian tube carcinoma. Postoperatively she received chemotherapy. Afterwards she underwent a staging laparotomy. Some months later, new chemotherapy regimens were instituted because of the presence of lymph node metastases. CONCLUSION: Malignancy should be included in the differential diagnosis of pelvic inflammatory disease.

Effects of minor constituents (non-glyceride compounds) of virgin olive oil on plasma lipid concentrations in male Wistar rats.

We aimed to assess the effects of minor constituents (MC) from virgin olive oil upon the plasma lipid profile of experimental animals. Therefore, 32 Wistar rats were fed for 6 weeks with one of four different diets with a similar fatty acid composition but different MC: high-oleic sunflower oil (HOSO), virgin olive oil (VOO), 400%-MC enriched olive oil (EOO) and MC poor (impoverished) olive oil (IOO). At the end of the week 6 of dietary treatment, blood samples were obtained for analysis of lipid composition. A statistically significant influence was observed upon both total HDL (1.593+/-0.4, 1.204+/-0.212, 0.991+/-0.244 and 0.827+/-0.279 mmol/L for EOO, HOSO, VOO and IOO, respectively, Kruskal-Wallis test, P<0.05) and HDL(2)cholesterol levels (1.16+/-0.26, 0.576+/-0.191, 0.585+/-0.216 and 0.583+/-0.207 mmol/L for EOO, HOSO, VOO and IOO, respectively, Kruskal-Wallis test, P<0.05). No statistically significant effect was observed upon LDL-cholesterol or triglycerides. Thus, MC supplementation has beneficial effects on HDL concentrations in Wistar rats.