RESUMO
Frontotemporal degeneration is a frequent cause of presenile dementia that makes up from 5 to 17% of autopsy-confirmed cases developed at the age of 70 years. Authors report a case of this disease, discuss the possible causes of its development and present the results of diffusion tensor magnetic resonance tractography. Clinical features of this case are practically isolated speech disturbance with the most likely domination of a semantic variant of primary progressive aphasia. Magnetic-resonance imaging has an important practical significance for this pathology due to the possibility of assessing atrophic zones. The use of DTI-tractography allows to extend diagnostic possibilities.
Assuntos
Imagem de Difusão por Ressonância Magnética/métodos , Imagem de Tensor de Difusão/métodos , Degeneração Lobar Frontotemporal/diagnóstico , Idoso , Doença de Alzheimer/etiologia , Afasia Primária Progressiva/complicações , Encéfalo/patologia , Degeneração Lobar Frontotemporal/complicações , Degeneração Lobar Frontotemporal/patologia , Humanos , Masculino , Testes NeuropsicológicosRESUMO
OBJECTIVE: To study chronobiological characteristics of ischemic stroke (II) and post stroke cognitive impairment (CI). MATERIAL AND METHODS: We examined 80 patients with acute ischemic stroke. The cognitive status, sleep quality, chronobiological parameters and night urinary level of 6-sulfatoxymelatonin were assessed. The clinical observation of the efficacy of melaxen treatment in intensive care unit was performed. RESULTS: The results of the study indicate the significance of social and environmental factors which determine the sleep-wake behavior in the development of pineal dysfunction. The pineal dysfunction probably underlies the development of stroke and accompanied neurodegenerative process. CONCLUSION: The use of melaxen in hyperacute stroke was associated with better recovery of circadian rhythms and rehabilitation results.
