[An efficiency study of transplantation of allogenic fibroblasts cultivated in collagen gel for the treatment of corneal burn defects in experiment]. / Izuchenie éffektivnosti transplantatsii kul'tivirovannykh allogennykh fibroblastov v kollagenovom gele pri lechenii ozhogovykh defektov rogovitsy v éksperimente.

The paper contains the results of using a mew method applicable to regulation of corneal regeneration, i.e. transplantation of allogenic fibroblasts cultivated in collagen gel within an experimental model of acute alkali corneal burns in rabbits. Two experimental stages, involving 120 animals, were undertaken. The above method was used, at stage 1, on day 2 after trauma and, at stage 2, it was applied in two weeks after ocular burns with profound corneal defects were inflicted. The clinical, morphological and immune-histochemical examinations were used to show a high efficiency of the method in healing the corneal burn wounds; the mechanism of the therapeutic action of the transplant components exerted on regeneration of the affected cornea was investigated; finally, good outlooks for using the discussed method in clinical practice were proven.

[Significance of the study of the pachymetric index in the evaluation of the process of eye adaptation to contact lenses]. / Znachenie issledovaniia pakhometricheskogo pokazatelia dlia otsenki protsessa adaptatsii glaza k kontaktnym linzam.

The authors have examined the thickness of the cornea in 270 patients with weak and moderate myopia during adaptation of the eye to soft or rigid contact lenses. They have revealed a linear correlation between the period of wearing the lens and the degree of the pachometric index change during adaptation of the eye to contact lenses. The maximum permissible period for daily wearing of contact lenses have been determined, not involving essential shifts in water-salt metabolism of the cornea. Optimal schedules for managing the adaptation process with rigid and soft contact lenses have been developed, based on the regularities of the corneal thickness changes related to the length of the lens wearing.

[Changes in the RNA content of the blood plasma in rats with Ehrlich ascitic cancer]. / Izmenenie soderzhaniia RNK v plazme krovi krys s astsitnym rakom Erlikha.

The RNA content in the blood plasma of tumour-bearing animals correlates with the tumour growth stage. The development of Ehrlich carcinoma in rats is followed by the RNA increase in the blood plasma, while spontaneous regression of the tumour is accompanied by a decrease of the RNA content in the blood plasma of rats with Ehrlich carcinoma almost to the normal level. The fractional spectrum of the blood plasma RNA in the tumour bearing rats is similar to that of the cell-free ascitic fluid of rats.

[Characteristics of nucleic acid secreted by Ehrlich ascites carcinoma cells]. / Kharakteristika nukleinovykh kislot, vydeliaemykh kletkami astsitnogo raka Erlikha.

Cells of Ehrlich ascite tumour secrete RNA to the medium. By ultracentrifugation within the gradient of cesium sulphate density the extracellular heterogenic RNA was found to contain the RNA-DNA hybrids. It is suggested that RNA secreted by the tumour cells participates in the tumour-host interactions.