[Generalized sporotrichosis. Study of a Mexican case treated with amphotericin B and ketoconazole]. / Sporotrichose généralisée. Etude d'un cas mexicain traité par l'amphotéricine B et le kétoconazole.

A case of deep sporotrichosis with cutaneous, articular, (...) and osseous lesions was observed in a Mexican patient following a beesting. The disease was associated with a complex pathological background namely diabetes. The pathogenic fungus Sporothrix schenckii was isolated in pure culture. The mycosis was successfully treated by amphotericin B and ketoconazole. Persisting enzymatic impairment was observed due to the sporotrichosis and/or underlying diseases.

Antimycobacterial antibodies in diffuse lepromatous leprosy detected by counterimmunoelectrophoresis.

By using the counterimmunoelectrophoresis (CIE) technic it was possible to demonstrate the presence of antimycobacterial antibodies in the sera of patients suffering from lepromatous leprosy. The antigen was prepared from isolated Mycobacterium lepraemurium. The technic was more reliable and quicker than Ouchterlony's classical double diffusion in gel. Clinical application of the method is therefore recommended.