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Sci Rep ; 7(1): 5259, 2017 07 12.
Artigo em Inglês | MEDLINE | ID: mdl-28701753

RESUMO

Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Bactérias/efeitos dos fármacos , Materiais Revestidos Biocompatíveis/química , Lasers , Nanopartículas Metálicas/química , Bactérias/efeitos da radiação , Ouro/química , Dióxido de Silício/química , Prata/química , Propriedades de Superfície
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