The impact of guidelines on peri-operative antibiotic administration.

A survey has shown that peri-operative antibiotic therapy was inappropriate in 83% of patients undergoing abdominal or arterial surgery. Missed doses at induction or postoperatively, a questionable choice of antibiotics and unnecessarily long postoperative courses were major problems. The introduction of formal guidelines was partially successful with appropriate prescribing improving from 17 to 60% of cases. There was, in addition, a marked reduction in prescribing costs.