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1.
Suicide Life Threat Behav ; 51(5): 1005-1014, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34184305

RESUMO

INTRODUCTION: While suicide attempts and deaths increase, research and assessment methods have stagnated in terms of increasing predictive power. Lexical analysis has been a useful method in descriptive suicide research, but may have utility for assessment and prediction. OBJECTIVE: The present study used lexical analysis to examine language differences across a spectrum of psychological distress, with death by suicide as the most extreme indicator. METHODS: Suicide writings were collected for 38 persons who died by suicide in two southern U.S. cities. Blog writings were collected from the "Depression" and "Suicide" categories of an online mental health discussion community and from food blogging communities (n = 38 each). Linguistic Inquiry and Word Count was used to calculate proportions of words that fell into lexical categories indicative of distress. RESULTS: One-way ANOVA revealed significant differences in first-person singular pronouns and words related to positive emotions, negative emotions, religion, and death. Suicide notes were found to use less frequent lexical markers of distress than depression and suicide ideation blogs, and more frequent positive emotion language than all comparison groups. CONCLUSION: The present findings suggest that deciding to take one's life may be associated with a decrease in distress, and possibly an increase in positive emotion, when compared to those experiencing depression and suicidal thoughts.


Assuntos
Blogging , Ideação Suicida , Culinária , Depressão , Emoções , Humanos , Idioma
2.
J Pers Disord ; 34(Suppl B): 64-83, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-31887101

RESUMO

Research has demonstrated mentalizing impairment associated with borderline personality disorder (BPD) in adolescents. However, mentalizing performance in adolescents with BPD has never been compared to that of psychiatric control and healthy control adolescents simultaneously. The present study aimed to (a) compare implicit and explicit mentalizing, and hypermentalizing errors in implicit mentalizing, across youth with BPD and psychiatric and healthy controls, and (b) evaluate the association of borderline features with mentalizing deficits over and above internalizing and externalizing. Psychiatric inpatients with BPD (n = 139), inpatient psychiatric controls (n = 310), and healthy adolescents (n = 134) completed two mentalizing tasks, an interview assessing BPD, and measures of psychopathology. Results showed that BPD specificity could be demonstrated only for implicit mentalizing and hypermentalizing. Explicit mentalizing deficits did not differ between BPD and psychiatric control groups. Borderline features had unique associations to implicit mentalizing and hypermentalizing, over and above internalizing and externalizing.


Assuntos
Transtorno da Personalidade Borderline , Mentalização , Adolescente , Humanos , Pacientes Internados
3.
Personal Disord ; 10(2): 132-142, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30829527

RESUMO

Borderline personality pathology is a serious mental illness characterized by pervasive interpersonal deficits that onset during adolescence. Risk factors for borderline personality pathology include maladaptive interpersonal dynamics within attachment relationships. Given the shift toward emphasizing romantic relationships during adolescence as an important attachment relationship with implications for healthy development, the current study aimed to evaluate the longitudinal and reciprocal relations between victimization in dating relationships and borderline pathology in the transition from late adolescence to early adulthood. A large sample of high school daters (N = 818; 58% female; Mage = 16.10 years, SDage = .78) were recruited to complete annual assessments of borderline personality features and dating violence victimization across 5 years. Results of a cross-lagged panel model revealed that primarily among girls, borderline features predicted increased levels of relational, psychological, and physical violence, whereas psychological and sexual violence predicted greater borderline features. The current findings provide the first evidence of a longitudinal association between victimization and borderline pathology in adolescence and suggest, particularly among girls, that interventions for borderline features have important implications for reducing dating violence victimization among adolescents and young adults. (PsycINFO Database Record (c) 2019 APA, all rights reserved).


Assuntos
Transtorno da Personalidade Borderline/epidemiologia , Vítimas de Crime/estatística & dados numéricos , Relações Interpessoais , Violência por Parceiro Íntimo/estatística & dados numéricos , Delitos Sexuais/estatística & dados numéricos , Adolescente , Adulto , Feminino , Humanos , Estudos Longitudinais , Masculino , Adulto Jovem
4.
Harv Rev Psychiatry ; 27(2): 75-86, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30676404

RESUMO

LEARNING OBJECTIVES: After participating in this activity, learners should be better able to:• Assess medication management in patients with borderline personality disorder (BPD)• Evaluate the role of deprescribing as an active intervention in patients with BPD treated with polypharmacy ABSTRACT: Psychopharmacology in borderline personality disorder (BPD) is complicated by comorbid disorders, substance use, sensitivity to side effects, risk of self-harm through medication misuse, and intense but transient symptoms. Patients' relationships with medications may range from tenuous to highly enmeshed, and may profoundly influence the response to treatment. For these reasons, awareness of current evidence and flexible approaches are particularly relevant to prescribing in BPD. In this narrative review, we illustrate the current status of medication management in BPD by focusing on polypharmacy. We use a single vignette to explore the limitations of prescribing multiple medications and the factors contributing to polypharmacy. With the same vignette, and using the framework of deprescribing, we describe how medication regimens can be reduced to a necessary minimum. Deprescribing, originally developed in geriatric medicine, is an active intervention that involves a risk-benefit analysis for each medication, keeping in mind the patient's medical and psychiatric status and his or her preferences and values. Deprescribing lends itself well to use in psychiatry and especially in BPD because of its emphasis on the patient's preferences and on repeated conversations to revisit and update decisions. In addition to elaborating on the deprescribing framework, we provide recommendations for conducting these critical discussions about medications in BPD, with particular attention to the patient's relationship to the medication. Finally, we summarize our recommendations and strategies for implementing flexible and responsive medication management for patients with BPD. We suggest areas of future research, including testing the efficacy of targeted intermittent medication treatments.


Assuntos
Transtorno da Personalidade Borderline/tratamento farmacológico , Desprescrições , Prescrições de Medicamentos , Participação do Paciente , Padrões de Prática Médica , Prescrições de Medicamentos/normas , Humanos , Padrões de Prática Médica/normas
5.
Neurosci Conscious ; 2019(1): niz017, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31908849

RESUMO

One aspect of selfhood that may have relevance for borderline personality disorder (BPD) is variation in sense of body ownership. We employed the rubber hand illusion to manipulate sense of body ownership in BPD. We extended previous research on illusory body ownership in BPD by testing: (i) two illusion conditions: asynchronous and synchronous stimulation, (ii) relationship between illusion experience and BPD symptoms, and (iii) relationship between illusion experience and maladaptive personality traits. We measured illusion strength (questionnaire responses), proprioceptive drift (perceived shift in physical hand position), BPD symptoms (Revised Diagnostic Interview for Borderlines score), and maladaptive personality traits (Personality Inventory for DSM-5) in 24 BPD and 21 control participants. For subjective illusion strength, we found main effects of group (BPD > healthy control, F(1, 43) = 11.94, P = 0.001) and condition (synchronous > asynchronous, F(1, 43) = 22.80, P < 0.001). There was a group × condition interaction for proprioceptive drift (F(1, 43) = 6.48, P = 0.015) such that people with BPD maintained illusion susceptibility in the asynchronous condition. Borderline symptom severity correlated with illusion strength within the BPD group, and this effect was specific to affective (r = 0.45, P < 0.01) and cognitive symptoms (r = 0.46, P < 0.01). Across all participants, trait psychoticism correlated with illusion strength (r = 0.44, P < 0.01). People with BPD are more susceptible to illusory body ownership than controls. This is consistent with the clinical literature describing aberrant physical and emotional experiences of self in BPD. A predictive coding framework holds promise to develop testable mechanistic hypotheses for disrupted bodily self in BPD.

6.
Biol Psychiatry ; 84(11): 838-845, 2018 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-30041970

RESUMO

BACKGROUND: Volatile interpersonal relationships are a core feature of borderline personality disorder (BPD) and lead to devastating disruption of patients' personal and professional lives. Quantitative models of social decision making and learning hold promise for defining the underlying mechanisms of this problem. In this study, we tested BPD and control subject weighting of social versus nonsocial information and their learning about choices under stable and volatile conditions. We compared behavior using quantitative models. METHODS: Subjects (n = 20 BPD, n = 23 control subjects) played an extended reward learning task with a partner (confederate) that requires learning about nonsocial and social cue reward probability (the social valuation task). Task experience was measured using language metrics: explicit emotions/beliefs, talk about the confederate, and implicit distress (using the previously established marker self-referentiality). Subjects' weighting of social and nonsocial cues was tested in mixed-effect regression models. Subjects' learning rates under stable and volatile conditions were modeled (Rescorla-Wagner approach) and group × condition interactions tested. RESULTS: Compared to control subjects, BPD subject debriefings included more mentions of the confederate and less distress language. BPD subjects also weighted social cues more heavily but had blunted learning responses to (nonsocial and social) volatility. CONCLUSIONS: This is the first report of patient behavior in the social valuation task. The results suggest that BPD subjects expect higher volatility than control subjects. These findings lay the groundwork for a neurocomputational dissection of social and nonsocial belief updating in BPD, which holds promise for the development of novel clinical interventions that more directly target pathophysiology.


Assuntos
Transtorno da Personalidade Borderline/psicologia , Cognição , Sinais (Psicologia) , Reconhecimento Psicológico , Percepção Social , Adulto , Estudos de Casos e Controles , Emoções , Feminino , Humanos , Masculino , Memória de Curto Prazo , Análise e Desempenho de Tarefas
7.
Psychiatry Res ; 260: 384-390, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29248760

RESUMO

Personal space regulation is a key component of effective social engagement. Personal space varies among individuals and with some mental health conditions. Simulated personal space intrusions in Borderline Personality Disorder (BPD) reveal larger preferred interpersonal distance in that setting. These findings led us to conduct the first test of live interpersonal distance preferences in symptoms in BPD. With direct observation of subjects' personal space behavior in the stop-distance paradigm, we found a 2-fold larger preferred interpersonal distance in BPD than control (n = 30, n = 23). We discuss this result in context of known biology and etiology of BPD. Future work is needed to identify neural circuits underlying personal space regulation in BPD, individual differences in preferred interpersonal distance in relation to specific symptoms and relationship to recovery status.


Assuntos
Transtorno da Personalidade Borderline/diagnóstico , Transtorno da Personalidade Borderline/psicologia , Relações Interpessoais , Espaço Pessoal , Distância Psicológica , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Adulto Jovem
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