Determination of the separation efficiencies of a single-stage cryogenic distillation setup to remove krypton out of xenon by using a (83m)Kr tracer method.

The separation of krypton and xenon is of particular importance for the field of direct dark matter search with liquid xenon detectors. The intrinsic contamination of the xenon with radioactive (85)Kr makes a significant background for these kinds of low count-rate experiments and has to be removed beforehand. This can be achieved by cryogenic distillation, a technique widely used in industry, using the different vapor pressures of krypton and xenon. In this paper, we present an investigation on the separation performance of a single stage distillation system using a radioactive (83m)Kr-tracer method. The separation characteristics under different operation conditions are determined for very low concentrations of krypton in xenon at the level of (83m)Kr/Xe = 1.9 ⋅ 10(-15), demonstrating, that cryogenic distillation in this regime is working. The observed separation is in agreement with the expectation from the different volatilities of krypton and xenon. This cryogenic distillation station is the first step on the way to a multi-stage cryogenic distillation column for the next generation of direct dark matter experiment XENON1T.

Spatially uniform calibration of a liquid xenon detector at low energies using (83m)Kr.

A difficult task with many particle detectors focusing on interactions below approximately 100 keV is to perform a calibration in the appropriate energy range that adequately probes all regions of the detector. Because detector response can vary greatly in various locations within the device, a spatially uniform calibration is important. We present a new method for calibration of liquid xenon (LXe) detectors, using the short-lived (83m)Kr. This source has transitions at 9.4 and 32.1 keV, and as a noble gas like Xe, it disperses uniformly in all regions of the detector. Even for low source activities, the existence of the two transitions provides a method of identifying the decays that is free of background. We find that at decreasing energies, the LXe light yield increases, while the amount of electric field quenching is diminished. Additionally, we show that if any long-lived radioactive backgrounds are introduced by this method, they will present less than 67x10(-6) events kg(-1) day(-1) keV(-1) in the next generation of LXe dark matter direct detection searches.

Thermoresponsive polymers as promising new materials for local radiotherapy.

We describe a novel thermoresponsive polymeric drug delivery system based on poly(N-isopropylacrylamide) with isotopically labellable end groups [l-tyrosinamide or diethylenetriaminepentaacetic acid (DTPA)] designed for local radiotherapy. The polymers are readily soluble in isotonic aqueous sodium chloride at room temperature and the phase separation is complete at body temperature as proved by DSC measurements. Sufficent binding capacity for radionuclides and chemical stability are demonstrated on 125I and 90Y-labelled polymers.

(83m)Kr radioactive source based on (83)Rb trapped in cation-exchange paper or in zeolite.

The mono-energetic conversion electrons from the decay of (83m)Kr represent a unique tool for energy calibration and systematic studies of the tritium beta spectrum measured in neutrino mass determination experiments. For this reason, the corresponding parent isotope was produced in reactions (nat)Kr(p,xn)(83)Rb. The behaviour of (83)Rb (T(1/2)=86.2d) and its daughter product (83m)Kr (T(1/2)=1.83h) was examined, when the (83)Rb was trapped in a cation-exchanger chromatographic paper or in zeolite. Using gamma spectroscopy measurements, recommendations for the production of a (83)Rb/(83m)Kr radionuclide generator based on these cation-exchangers and suitable for the neutrino mass determination experiment KATRIN were deduced.

A new internal target system for production of (211)At on the cyclotron U-120M.

The alpha emitter (211)At is a radionuclide with good potential for use in the therapy of smaller tumours and metastases. However, limited availability of this radionuclide hinders development of this application and the research of astatine chemistry in general. In this general context we have designed and tested a new internal target system. A thin bismuth layer (3-5 microm) was evaporated onto a light target backing (7.5 g) and irradiated at 0.5-1.5 degrees angles with 29.5 MeV alpha particles beam of intensity up to 30 microA. The backing was then released from the target holder and used directly for astatine separation via dry distillation. Astatine condensed on the Teflon capillary walls was then eluted into 150-250 microl of methanol. The saturation yield was found to be ca. 400 MBq/microA, and the radionuclidic purity of (211)At acceptable for medical applications (activity ratio (210)At/(211)At<10(-3) at EOB). The overall separation yield was 65-75%.