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1.
Pol Merkur Lekarski ; 26(156): 645-8, 2009 Jun.
Artigo em Polonês | MEDLINE | ID: mdl-19711734

RESUMO

Cystic changes within CNS, revealed by computed tomography or magnetic resonance imaging, pose difficult diagnostic and therapeutic problem. We present two patients with primary diagnosis of parasitic cysts of CNS, in whom neoplastic etiology was finally confirmed. Differential diagnosis of cystic foci should from the beginning include not only parasitic infections, but also neoplastic diseases, which are much more frequent in Poland at present and in which prolonged diagnostic process and delayed treatment is highly unfavorable.


Assuntos
Neoplasias Encefálicas/diagnóstico , Carcinoma/diagnóstico , Cistos/diagnóstico , Encefalopatias/diagnóstico , Neoplasias Encefálicas/patologia , Carcinoma/patologia , Infecções Parasitárias do Sistema Nervoso Central/diagnóstico , Diagnóstico Diferencial , Evolução Fatal , Feminino , Humanos , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
2.
Folia Morphol (Warsz) ; 63(1): 79-81, 2004 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15039906

RESUMO

The enlargement of the thyroid is, in general, benign in origin and due to nodular goitre. Follicular cellular proliferation of thyroid nodules has been increasingly observed recently. With fine needle aspiration biopsy (FNAB) this is classified as a follicular tumour. These lesions present various patterns of vascularisation in ultrasound examination. The aim of the study was to establish the relation between follicular nodule vascularisation and the proliferative activity of various types of follicular cell. According to the manner of proliferation, patients were divided into groups as follows: (I). patients with hyperplastic nodules (46 cases), (II). patients with follicular adenoma (42 cases), and (III). patients with follicular cancer (9 cases). In each case B-mode sonography, Power Doppler, sonographically guided FNAB (S-FNAB), morphological examination and morphometry were performed. The proliferative activity was detected with immunohistochemical methods (PCNA, Ki 67 and MPM2) to determine the so-called "proliferative index". The study revealed increased proliferative activity in tumours of malignant origin and increased vascularisation in coexistence with increased proliferation of the follicular cells. As assessed by Power Doppler, an increased flow pattern in the centre of the nodules correlates with increased proliferative activity. The results suggest that Power Doppler examination could be helpful in selecting nodules for FNAB, especially in multinodular goitre.


Assuntos
Adenocarcinoma Folicular/irrigação sanguínea , Adenoma/irrigação sanguínea , Proteínas de Ciclo Celular , Nódulo da Glândula Tireoide/irrigação sanguínea , Adenocarcinoma Folicular/química , Adenocarcinoma Folicular/diagnóstico , Adenoma/química , Adenoma/diagnóstico , Adolescente , Adulto , Idoso , Biomarcadores Tumorais/análise , Biópsia por Agulha Fina , Divisão Celular , Feminino , Humanos , Imuno-Histoquímica , Antígeno Ki-67/análise , Cinesinas , Masculino , Pessoa de Meia-Idade , Fosfoproteínas/análise , Antígeno Nuclear de Célula em Proliferação/análise , Nódulo da Glândula Tireoide/química , Nódulo da Glândula Tireoide/diagnóstico , Ultrassonografia Doppler
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