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1.
J Periodontal Implant Sci ; 53(4): 269-282, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36468488

RESUMO

PURPOSE: Dental fear hinders patients from receiving appropriate dental treatment. In particular, the noise generated by high-speed air turbines and ultrasonic scalers can adversely affect patients. Many efforts have been made to reduce the discomfort caused by noise, but no methods are definitively recommended. The purpose of this study was to determine the efficacy of active noise-canceling (ANC) headphones in reducing the pain and discomfort associated with dental scaling. METHODS: Fifty-five patients requiring scaling and root planing, aged ≥19 years and showing no auditory problems, were included. Scaling was performed for the bilateral maxillary molars and premolars while patients wore headphones, with ANC turned either on or off. The degree of noise and pain reduction in the on and off conditions were surveyed using a visual analog scale (VAS). The Wilcoxon signed-rank test was performed to compare noise- and pain-related discomfort with ANC turned on and off. RESULTS: The sample included 28 men and 27 women with a mean age of 45.45±13.12 years. The average noise-related discomfort score was 3.84±2.12 and 2.95±1.99 when noise-canceling was turned off and on, respectively, with a statistically significant difference (P<0.05). Similarly, the average pain-related discomfort score was 3.78±2.00 and 3.09±1.96 when noise-canceling was turned off and on, respectively, which was a statistically significant difference (P<0.05). CONCLUSIONS: The use of ANC headphones seems to reduce the discomfort caused by noise and pain in patients undergoing scaling. TRIAL REGISTRATION: Clinical Research Information Service Identifier: KCT0007093.

2.
J Periodontal Implant Sci ; 52(3): 194-205, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35775695

RESUMO

PURPOSE: This study aimed to determine the long-term outcomes after peri-implantitis treatment and the factors affecting these outcomes. METHODS: This study included 92 implants in 45 patients who had been treated for peri-implantitis. Clinical data on the characteristics of patients and their implants were collected retrospectively. The change in the marginal bone level was calculated by comparing the baseline and the most recently obtained (≥3 years after treatment) radiographs. The primary outcome variable was progression of the disease after the treatment at the implant level, which was defined as further bone loss of >1.0 mm or implant removal. A 2-level binary logistic regression analysis was used to identify the effects of possible factors on the primary outcome. RESULTS: The mean age of the patients was 58.7 years (range, 22-79 years). Progression of peri-implantitis was observed in 64.4% of patients and 63.0% of implants during an observation period of 6.4±2.7 years (mean±standard deviation). Multivariable regression analysis revealed that full compliance to recall visits (P=0.019), smoking (P=0.023), placement of 4 or more implants (P=0.022), and marginal bone loss ≥4 mm at baseline (P=0.027) significantly influenced the treatment outcome. CONCLUSIONS: The long-term results of peri-implantitis treatment can be improved by full compliance on the part of patients, whereas it is impaired by smoking, placement of multiple implants, and severe bone loss at baseline. Encouraging patients to stop smoking and to receive supportive care is recommended before treatment.

3.
J Periodontal Implant Sci ; 52(3): 230-241, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35775698

RESUMO

PURPOSE: The purpose of this study was to evaluate failed implants and reimplantation survival and to identify the relative risk factors for implant re-failure. METHODS: Ninety-one dental implants were extracted between 2006 and 2020 at the National Health Insurance Service Ilsan Hospital, including 56 implants in the maxilla and 35 implants in the mandible that were removed from 77 patients. Patient information (e.g., age, sex, and systemic diseases) and surgical information (e.g., the date of surgery and location of the implants and bone grafts) were recorded. If an implant prosthesis was used, prosthesis information was also recorded. RESULTS: In total, 91 first-time failed dental implants in 77 patients were analyzed. Of them, 69 implants in 61 patients received reimplantation after failure. Sixteen patients (22 implants) refused reimplantation or received reimplantation at a different site. Eight of the 69 reimplants failed again. The 1-year survival rate of the 69 reimplants was 89.4%. Age at reimplantation and smoking significantly increased the risk of reimplantation failure. However, a history of taking anti-thrombotic agents showed a statistically significant negative association with reimplantation failure. Of the failed implants, 66% showed early failure and 34% showed late failure of the initial implantation. All 8 re-failed implants showed early failure. Only 3 of these 8 failed reimplants were re-tried and the second reimplants all survived. CONCLUSIONS: The total survival rate of implants, which included reimplants and second reimplants was 99.2%, although the survival rate of the initial implantations was 96.3%. Previous failure did not affect the success of the next trial. Reimplantation failure was more strongly affected by patient factors than by implant factors. Therefore, each patient's specific factors need to be meticulously controlled to achieve successful reimplantation.

4.
J Prosthet Dent ; 125(2): 273-278, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32336540

RESUMO

STATEMENT OF PROBLEM: Implant-supported prostheses have typically been retained by cement or screws, each of which has advantages and disadvantages. Two new types of prosthesis with complementary advantages and disadvantages have been proposed: the screw- and cement-retained prosthesis, which combines cement and screw retention, and the antiloosening inner-post screw (ALIPS) type, which uses lateral screws. Both esthetic and functional factors should be considered for anterior prostheses; however, clinical studies of the complication rates of these designs are lacking. PURPOSE: The purpose of this retrospective clinical study was to evaluate the complications of dental implant-supported restorations with various prosthetic types in the anterior region and to analyze other factors that affect complications. MATERIAL AND METHODS: This study included 51 patients who had 83 implants placed in the anterior region by a single clinician between August 2009 and December 2016. Surgical and prosthetic features were recorded, and implant complications were analyzed. RESULTS: There were 45 (55.4%) cement-retained implants, 5 (6.0%) screw- and cement-retained prosthesis implants, and 32 (38.6%) ALIPS-retained implants. Peri-implant mucositis was observed most frequently in the ALIPS type (21.9%), but the biological complications did not differ significantly with the prosthetic type. The most common mechanical complication was loss of retention in the cement type of prosthesis (30.4%) and screw loosening in the ALIPS type (43.8%). Implant complications varied with position (maxilla or mandible) and implantation timing (period from tooth extraction to implant placement). CONCLUSIONS: The complications of implants placed in the anterior region were affected by different factors but did not differ significantly with the type of the retention.


Assuntos
Implantes Dentários , Falha de Restauração Dentária , Implantes Dentários/efeitos adversos , Retenção em Prótese Dentária , Prótese Dentária Fixada por Implante/efeitos adversos , Estética Dentária , Humanos , Estudos Retrospectivos
5.
J Periodontal Implant Sci ; 50(4): 260-267, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32643329

RESUMO

PURPOSE: The aim of this study was to compare the prevalence, amount, and rate of supraeruption of the maxillary second molar according to sex, age, and history of periodontitis. METHODS: Data were collected retrospectively from the charts and panoramic radiographs of 65 patients who were scheduled to undergo implant placement at the site of the mandibular second molar. The amount of supraeruption of the maxillary second molar and the alveolar bone level of the neighboring teeth were measured on digital panoramic radiographs. The prevalence was evaluated in each group, and univariate and multivariate logistic regression analyses were used to identify factors influencing the prevalence of supraeruption. The amount and the rate of supraeruption were compared between pairs of groups using the Mann-Whitney U test. For all tests, P values <0.05 were considered to indicate statistical significance. RESULTS: Supraeruption occurred in 78% of the patients. The prevalence of supraeruption was affected by sex, age, and history of periodontitis. The mean amount of supraeruption was 0.91 mm and the mean rate of supraeruption was 0.14 mm/month. The amount and the rate of supraeruption showed no significant differences according to sex, age, or the distance from the cementoenamel junction to the alveolar bone crest (P>0.05). CONCLUSIONS: These results show that the amount of supraeruption on the maxillary second molar was similar to the thickness of the enamel on the occlusal surface. When a single implant is scheduled to be placed on the mandibular second molar, supraeruption of the antagonist should be considered.

6.
J Periodontal Implant Sci ; 49(4): 248-257, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31485375

RESUMO

PURPOSE: The purpose of this retrospective study was to investigate the relationships of types of dental insurance coverage in Korea with sociodemographic characteristics and the prevalence of systemic and oral diseases, as well as to evaluate the socioeconomic impact of Korean dental insurance policies. METHODS: Sample cohort data from 2006 to 2015 were obtained from the National Health Insurance Service. Patients were divided into 2 groups. The exposed group comprised patients who received insurance benefits for complete dentures, removable partial dentures, and implant care, while the control group comprised patients who did not receive these benefits. The type of insurance coverage and the prevalence of systemic and oral diseases were compared between the 2 groups. RESULTS: Patients who received benefits in the form of complete dentures, removable partial dentures, and implants had similar sociodemographic characteristics in terms of sex, age, income quintile, and type of insurance coverage to the control group. The prevalence of hypertension, anemia, renal disease, rheumatoid arthritis, osteoporosis, asthma, and cerebral infarction was higher in the exposed group than in the control group (P<0.05). The prevalence of periodontal diseases and dental caries was also higher in the exposed group. CONCLUSIONS: Korean dental health insurance policy has been beneficial for the medical expenses of low-income and elderly people suffering from a cost burden due to systemic diseases. However, since there is a tendency to avoid invasive interventions in older patients due to the high risk of systemic diseases, insurance coverage of dentures may be more helpful from a socioeconomic perspective than coverage of dental implant treatments.

7.
J Periodontal Implant Sci ; 48(5): 317-325, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30405939

RESUMO

PURPOSE: We investigated correlations between the findings of oral examinations and panoramic radiography in order to determine the efficacy of using panoramic radiographs in screening examinations. METHODS: This study included patients who visited dental clinics at National Health Insurance Service (NHIS) Ilsan Hospital for checkups during 2009-2015 and underwent panoramic radiographic examinations within 1 year prior to the oral examinations. Among the 48,006 patients who received checkups, 1,091 were included in this study. The data were evaluated using the Cohen kappa and interrater agreement coefficients. Accuracy, sensitivity, and specificity were calculated using data from the panoramic radiographs as true positive diagnoses. RESULTS: The interrater agreement coefficient for occlusal caries was 28.8%, and the Cohen kappa coefficient was 0.043 between the oral and panoramic radiographic examinations. Root caries and subgingival calculus were only found on the radiographs, while gingival inflammation was found only by the oral examinations. The oral examinations had a specificity for detecting occlusal dental caries of 100%, while their sensitivity for proximal dental caries and supragingival calculus was extremely low (14.0% and 18.3%, respectively) compared to the panoramic radiographic examinations. The oral examinations showed a relatively low sensitivity of 66.2% and a specificity of 43.7% in detecting tooth loss compared with panoramic radiography. CONCLUSIONS: Panoramic radiography can provide information that is difficult to obtain in oral examinations, such as root caries, furcation involvement, and subgingival calculus, which are factors that can directly affect the survival rate of teeth. It therefore seems reasonable and necessary to add panoramic radiography to large-scale health checkup programs such as that provided by the NHIS.

8.
Clin Implant Dent Relat Res ; 20(5): 799-805, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30048041

RESUMO

BACKGROUND: Marginal bone loss (MBL) is considered an important determinant of implant success, and establishing the peri-implant biological width has been regarded to influence MBL around implants. However, few studies have attempted to show the relationship between the crown/abutment gap and MBL. PURPOSE: To evaluate the effect of the prosthetic abutment height on MBL of dental implants. MATERIALS AND METHODS: This study evaluated data which were retrospectively collected through chart and panoramic radiographs of 145 patients (78 males and 67 females; aged 19 to 79 years, mean age 54.1 years) in whom 273 implants were placed by a single clinician between June 2009 and December 2014. The abutment height and the bone level were measured in digital panorama radiographs. All correlations between abutment height and MBL were analyzed using Spearman's test (P < .05). RESULTS: The 273 implants comprised 126 in 67 female patients and 147 in 78 male patients. The mean age of the patients was 54.1 years (range 19-79 years). The prevalence of MBL and the mean MBL decreased as the abutment height increased. Spearman's test showed a significant negative correlation between abutment height and MBL (P < .05). CONCLUSION: The present study suggests that implants with a higher prosthetic abutment show less MBL, with the abutment height recommended to not exceed 4 mm.


Assuntos
Perda do Osso Alveolar/etiologia , Dente Suporte/efeitos adversos , Projeto do Implante Dentário-Pivô/efeitos adversos , Adulto , Idoso , Perda do Osso Alveolar/diagnóstico por imagem , Implantação Dentária Endóssea/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia Panorâmica , Estudos Retrospectivos , Adulto Jovem
9.
J Adv Prosthodont ; 6(6): 512-20, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25551012

RESUMO

PURPOSE: The purpose of this study was to assess the surface characteristics and the biocompatibility of zirconium (Zr) coating on Ti-6Al-4V alloy surface by radio frequency (RF) magnetron sputtering method. MATERIALS AND METHODS: The zirconium films were developed on Ti-6Al-4V discs using RF magnetron sputtering method. Surface profile, surface composition, surface roughness and surface energy were evaluated. Electrochemical test was performed to evaluate the corrosion behavior. Cell proliferation, alkaline phosphatase (ALP) activity and gene expression of mineralized matrix markers were measured. RESULTS: SEM and EDS analysis showed that zirconium deposition was performed successfully on Ti-6Al-4V alloy substrate. Ti-6Al-4V group and Zr-coating group showed no significant difference in surface roughness (P>.05). Surface energy was significantly higher in Zr-coating group than in Ti-6Al-4V group (P<.05). No difference in cell morphology was observed between Ti-6Al-4V group and Zr-coating group. Cell proliferation was higher in Zr-coating group than Ti-6Al-4V group at 1, 3 and 5 days (P<.05). Zr-coating group showed higher ALP activity level than Ti-6Al-4V group (P<.05). The mRNA expressions of bone sialoprotein (BSP) and osteocalcin (OCN) on Zr-coating group increased approximately 1.2-fold and 2.1-fold respectively, compared to that of Ti-6Al-4V group. CONCLUSION: These results suggest that zirconium coating on Ti-6Al-4V alloy could enhance the early osteoblast responses. This property could make non-toxic metal coatings on Ti-6Al-4V alloy suitable for orthopedic and dental implants.

10.
J Adv Prosthodont ; 5(4): 402-8, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24353877

RESUMO

PURPOSE: The aim of this study was to evaluate the surface properties and in vitro bioactivity to osteoblasts of magnesium and magnesium-hydroxyapatite coated titanium. MATERIALS AND METHODS: Themagnesium (Mg) and magnesium-hydroxyapatite (Mg-HA) coatings on titanium (Ti) substrates were prepared by radio frequency (RF) and direct current (DC) magnetron sputtering.The samples were divided into non-coated smooth Ti (Ti-S group), Mg coatinggroup (Ti-Mg group), and Mg-HA coating group (Ti-MgHA group).The surface properties were evaluated using scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The surface roughness was evaluated by atomic force microscopy (AFM). Cell adhesion, cell proliferation and alkaline phosphatase (ALP) activity were evaluated using MC3T3-E1 cells. Reverse transcription polymerase chain reaction (RT-PCR) analysis was performed. RESULTS: Cross-sectional SEM images showed that Mg and Mg-HA depositionson titanium substrates were performed successfully. The surface roughness appeared to be similaramong the three groups. Ti-MgHA and Ti-Mg group had improved cellular responses with regard to the proliferation, alkaline phosphatase (ALP) activity, and bone-associated markers, such as bone sialoprotein (BSP) and osteocalcin (OCN) mRNA compared to those of Ti-S group. However, the differences between Ti-Mg group and Ti-MgHA group were not significant, in spite of the tendency of higher proliferation, ALP activity and BSP expression in Ti-MgHA group. CONCLUSION: Mg and Mg-HAcoatings could stimulate the differentiation into osteoblastic MC3T3-E1 cells, potentially contributing to rapid osseointegration.

11.
J Periodontal Implant Sci ; 43(4): 198-205, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24040573

RESUMO

PURPOSE: The aim of this study was to evaluate the surface properties and biological response of an anodized titanium surface by cell proliferation and alkaline phosphatase activity analysis. METHODS: Commercial pure titanium (Ti) disks were prepared. The samples were divided into an untreated machined Ti group and anodized Ti group. The anodization of cp-Ti was formed using a constant voltage of 270 V for 60 seconds. The surface properties were evaluated using scanning electron microscopy, X-ray photoelectron spectroscopy, and an image analyzing microscope. The surface roughness was evaluated by atomic force microscopy and a profilometer. The contact angle and surface energy were analyzed. Cell adhesion, cell proliferation, and alkaline phosphatase activity were evaluated using mouse MC3T3-E1 cells. RESULTS: The anodized Ti group had a more porous and thicker layer on its surface. The surface roughness of the two groups measured by the profilometer showed no significant difference (P>0.001). The anodized Ti dioxide (TiO2) surface exhibited better corrosion resistance and showed a significantly lower contact angle than the machined Ti surface (P>0.001). Although there was no significant difference in the cell viability between the two groups (P>0.001), the anodized TiO2 surface showed significantly enhanced alkaline phosphatase activity (P<0.001). CONCLUSIONS: These results suggest that the surface modification of Ti by anodic oxidation improved the osteogenic response of the osteoblast cells.

12.
J Prosthet Dent ; 109(2): 95-105, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23395335

RESUMO

STATEMENT OF PROBLEM: Ti-10Ta-10Nb alloy is a promising alloy for metal ceramic crowns because of its good corrosion resistance and low cytotoxicity. However, more information is needed on the bond strength between this alloy and porcelain. PURPOSE: The purpose of this study was to compare the surface morphology, surface roughness, and bond strength of a Ti-10Ta-10Nb alloy, pure Ti, and a Ti-6Al-4V alloy. MATERIAL AND METHODS: Ti-10Ta-10Nb, pure Ti, and Ti-6Al-4V specimens (25 × 3 × 0.55 mm plate) were prepared and then divided into 6 groups (n=8) according to surface treatment. Group P (control group) was polished with SiC paper. Groups S50 and S250 were airborne-particle abraded with 50 µm and 250 µm aluminum oxide powder. Group HCl was immersed in 10% HCl aqueous solution, and Group HF was immersed in 17% HNO(3)/HF solution. Group TiN was coated with TiN. Atomic force microscopy was used to observe the surface roughness of the metal surface. Scanning electron microscopy was used to analyze the surface profile. A 3-point bending test was performed to evaluate the bond strength. Two-way analysis of variance (ANOVA) was performed to compare the roughness and bond strength and statistical differences were revealed by the Bonferroni post hoc test (α=.05). RESULTS: There were significant differences in the surface roughness, surface profile, and bond strength of the Ti alloys according to the surface treatments. The groups with the higher mean surface roughness showed higher bond strength, but surface profile had a larger effect on the bond strength than surface roughness. Moreover, the bond strength of the Ti-10Ta-10Nb alloy was high. CONCLUSIONS: Ti-10Ta-10Nb would be more suitable for a metal ceramic crown than pure Ti or Ti-6Al-4V, which have limited use because of their low bond strength to porcelain.


Assuntos
Colagem Dentária , Porcelana Dentária/química , Ligas Metalo-Cerâmicas/química , Titânio/química , Condicionamento Ácido do Dente/métodos , Ligas , Óxido de Alumínio/química , Compostos Inorgânicos de Carbono/química , Ligas Dentárias/química , Corrosão Dentária/métodos , Materiais Dentários/química , Polimento Dentário/métodos , Análise do Estresse Dentário/instrumentação , Módulo de Elasticidade , Temperatura Alta , Humanos , Ácido Clorídrico/química , Ácido Fluorídrico/química , Teste de Materiais , Microscopia de Força Atômica , Microscopia Eletrônica de Varredura , Nióbio/química , Ácido Nítrico/química , Maleabilidade , Compostos de Silício/química , Estresse Mecânico , Propriedades de Superfície , Tantálio/química , Fatores de Tempo
13.
J Periodontol ; 84(8): 1221-9, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23106504

RESUMO

BACKGROUND: The development of host-modulatory agents with low risk of adverse effects has been needed to treat periodontitis, a chronic inflammatory disease. A botanical mixture of extracts from two natural substances, Panax notoginseng and Rehmannia glutinosa Libosch, was developed as a novel botanical agent synthesized with anti-inflammatory effect. The aim of this study is to evaluate the effects of the botanical mixture on the release of inflammatory cytokines and its inhibitory effect on lipopolysaccharide (LPS)-induced alveolar bone loss (ABL) in a rat model. METHODS: Cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2yl)-5(3-carboxymethoxyphenol)-2-(4-sulfophenyl)-2H-tetrazolium assay using human gingival fibroblast (hGF) and human periodontal ligament (hPDL) cells. Human acute monocytic leukemia cell line and hGF cells were cultured to assay tumor necrosis factor (TNF)-α and interleukin (IL)-6, respectively. Microcomputed tomography analysis and immunofluoresence analysis were performed to evaluate the efficacy of the botanical mixture to inhibit the destruction of alveolar bone and connective tissue in a rat model. RESULTS: The botanical mixture is cytotoxic at concentrations exceeding 2.5 mg/mL (P <0.05). Based on the results from cytotoxicity assay, it can be determined that the pharmacologic ranges of the botanical mixture to be used in all subsequent in vitro and in vivo experiments. The botanical mixture reduced the release of TNF-α and IL-6 from human monocytic cells and hGF cells in a dose-dependent manner (P <0.05). The administration of the botanical mixture significantly reduced the alveolar bone loss in a rat model (P <0.05). In groups treated with the botanical mixture, matrix metalloproteinase (MMP)-9 was detected along the alveolar bone crest (ABC), but not around the gingival connective tissue, while in the group with LPS-induced ABL, pronounced expression of MMP-9 around the ABC, periodontal ligament, and gingival connective tissue was found. CONCLUSIONS: The botanical mixture showed a potential adjunctive effect in the treatment of periodontitis. However, the present findings are obtained in vitro and in a rat model, so further clinical study is needed for its clinical application.


Assuntos
Perda do Osso Alveolar/prevenção & controle , Anti-Inflamatórios/uso terapêutico , Lipopolissacarídeos/efeitos adversos , Fitoterapia/métodos , Extratos Vegetais/uso terapêutico , Processo Alveolar/efeitos dos fármacos , Animais , Anti-Inflamatórios/toxicidade , Técnicas de Cultura de Células , Linhagem Celular Tumoral , Tecido Conjuntivo/efeitos dos fármacos , Citocinas/efeitos dos fármacos , Modelos Animais de Doenças , Relação Dose-Resposta a Droga , Medicamentos de Ervas Chinesas/uso terapêutico , Medicamentos de Ervas Chinesas/toxicidade , Escherichia coli , Fibroblastos/efeitos dos fármacos , Gengiva/citologia , Gengiva/efeitos dos fármacos , Humanos , Interleucina-6/análise , Masculino , Metaloproteinase 9 da Matriz/efeitos dos fármacos , Monócitos/efeitos dos fármacos , Monócitos/imunologia , Ligamento Periodontal/efeitos dos fármacos , Extratos Vegetais/toxicidade , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Rehmannia , Fator de Necrose Tumoral alfa/efeitos dos fármacos
14.
J Periodontal Implant Sci ; 42(6): 248-55, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23346470

RESUMO

PURPOSE: The aim of the present study was to evaluate the biological response of alkali- and heat-treated titanium-8tantalum-3niobium surfaces by cell proliferation and alkaline phosphatase (ALP) activity analysis. METHODS: Commercial pure titanium (group cp-Ti) and alkali- and heat-treated titanium-8tantalum-3niobium (group AHT) disks were prepared. The surface properties were evaluated using scanning electron microscopy, energy dispersed spectroscopy and X-ray photoelectron spectroscopy (XPS). The surface roughness was evaluated by atomic force microscopy and a profilometer. The contact angle and surface energy were also analyzed. The biological response of fetal rat calvarial cells on group AHT was assessed by cell proliferation and ALP activity. RESULTS: Group AHT showed a flake-like morphology microprofile and dense structure. XPS analysis of group AHT showed an increased amount of oxygen in the basic hydroxyl residue of titanium hydroxide groups compared with group cp-Ti. The surface roughness (Ra) measured by a profilometer showed no significant difference (P>0.05). Group AHT showed a lower contact angle and higher surface energy than group cp-Ti. Cell proliferation on group AHT surfaces was significantly higher than on group cp-Ti surfaces (P<0.05). In comparison to group cp-Ti, group AHT enhanced ALP activity (P<0.05). CONCLUSIONS: These results suggest that group AHT stimulates osteoblast differentiation.

15.
J Periodontol ; 83(6): 753-6, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22050549

RESUMO

BACKGROUND: Squamous cell carcinoma (SCC) is the most common malignant neoplasm of the oral cavity. The clinical features of gingival SCC include alveolar bone loss and erythematous lesion. Therefore, gingival SCC sometimes presents as advanced periodontitis. This case report describes a patient diagnosed with gingival SCC after the extraction of molars presenting as being affected by localized severe periodontitis. METHODS: The patient was a 61-year-old man whose chief complaint was pain in the left maxillary area. Clinical and radiographic examinations revealed common findings of a periodontal abscess on the left maxillary first and second molars. These teeth were extracted based on a diagnosis of a periodontal abscess. Three months later, a rapidly growing exophytic soft tissue mass was observed, and a biopsy of the mass was performed. RESULTS: According to the biopsy, the final diagnosis was a well-differentiated SCC. The patient was treated with a partial maxillectomy of the left maxilla and split-thickness skin graft. Two years after treatment, the patient remained free of recurrence. CONCLUSIONS: Gingival SCC is quite different from other forms of SCC, mimicking localized periodontal disease. Therefore, it can be misdiagnosed as localized periodontal disease and is generally discovered after extracting teeth. Therefore, clinicians must diagnose these lesions carefully and follow up with the patient after tooth extraction.


Assuntos
Carcinoma de Células Escamosas/diagnóstico , Periodontite Crônica/diagnóstico , Neoplasias Gengivais/diagnóstico , Perda do Osso Alveolar/diagnóstico , Diagnóstico Diferencial , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Dente Molar/patologia , Abscesso Periodontal/diagnóstico , Bolsa Periodontal/diagnóstico , Extração Dentária
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