1.
Parkinsonism Relat Disord
; 18(4): 391-3, 2012 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22243834
RESUMO
Parkinson's disease (PD) is a neurodegenerative disorder comprising both motor and cognitive disability. The pathogenesis of the disease is still unclear; however, neuroinflammation seemed to play a role. A recent genome-wide association study (GWAS) reported an association between HLA-DRA rs3129882 and the development of PD in Caucasian populations. In this study, we observe no association between this single nucleotide polymorphism and PD in a Taiwanese population. The possible reasons include different ethnicity with genomic differences and environmental factors in different geographical regions.