1.
Breast J
; 24(2): 212-213, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28741803
Assuntos
Neoplasias da Mama/radioterapia , Radiodermite/etiologia , Síndrome de Sweet/etiologia , Idoso , Feminino , Glucocorticoides/administração & dosagem , Humanos , Prednisolona/administração & dosagem , Radiodermite/tratamento farmacológico , Radiodermite/patologia , Radioterapia/efeitos adversos , Síndrome de Sweet/tratamento farmacológico , Síndrome de Sweet/patologia
2.
Breast J
; 23(6): 747-749, 2017 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28892216
RESUMO
Breast cancer treatment involving ionizing radiation causes characteristic radiation dermatitis in the majority of patients. The DNA damaging effects of radiation can rarely predispose to primary inflammatory dermatoses, such as pemphigus vulgaris. In such cases, the disease presents with all the hallmarks of the primary dermatosis, but the eruption is limited to the field of irradiation and is often amenable to treatment. In contrast, occurrence of generalized pemphigus vulgaris in this setting may mean cancer recurrence. The mechanism by which radiotherapy induces localized disease remains unknown, but there is likely a loss of self-tolerance which maybe coupled to antigen exposure.